All 413 actors in both Castle and Grey's Anatomy
413 actors have appeared in both Castle and Grey's Anatomy, across 640 episodes. The most-credited is Jason George, Charles Kelvin in Castle and Dr. Ben Warren in Grey's Anatomy.
| Actor | In Castle | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Jason George | Charles Kelvin | Dr. Ben Warren | 1 | 90 |
| Maya Stojan | Tory Ellis | Tatiana Flauto | 26 | 1 |
| Tina Majorino | Reese Harmon | Dr. Heather Brooks | 1 | 22 |
| Samantha Sloyan | Pam | Dr. Penelope Blake | 1 | 19 |
| Arye Gross | Dr. Sidney Perlmutter | Adam Morris | 17 | 1 |
| Grace Rowe | Reporter #1 | Paramedic Grace | 1 | 17 |
| Justin Bruening | "Rocket" Rob Tredwyck | Matthew Taylor | 1 | 17 |
| Abigail Spencer | Sarah Reed / Lauren Branston | Dr. Megan Hunt | 1 | 15 |
| Kelly McCreary | Kelly Jane | Dr. Margaret "Maggie" Pierce | 1 | 13 |
| Sarah Drew | Chloe Richardson | Dr. April Kepner | 1 | 13 |
| Gloria Garayua | Kristina Curtis | Dr. Graciella Guzman | 1 | 24 |
| Sunkrish Bala | Vikram Singh | Steve Murphy | 9 | 1 |
| Rebecca Field | Marilyn Kane | Sabine McNeil | 1 | 7 |
| Joe Williamson | Charlie Green | Dr. Pierce Halley | 1 | 22 |
| Caterina Scorsone | Joanne Delgado | Dr. Amelia Shepherd | 1 | 6 |
| Joy Osmanski | Liz Bell | Intern Lucy | 1 | 11 |
| Mitch Pileggi | Hans Brauer | Larry Jennings | 1 | 9 |
| Sam Page | Brian Elliott | Sam Sutton | 1 | 4 |
| Hilarie Burton Morgan | Kay Cappuccio | Dr. Lauren Boswell | 1 | 3 |
| Jordan Belfi | Beau Randolph | Nick | 2 | 2 |
| Phil LaMarr | Dr. Holloway | Steve Duncan | 3 | 1 |
| Robert Picardo | Dr. Clark Murray | Mr. Nelligan | 2 | 2 |
| Kathleen M. Darcy | Dawn Craig | Anesthesiologist | 1 | 10 |
| Ann Cusack | Rita | Amy Polus | 2 | 1 |
| Joshua Bitton | Grant "Sully" Sullivan | Harry Adkins | 2 | 1 |
| Jonathan Adams | Vulcan Simmons | Dewayne Griffith | 3 | 2 |
| Scott Elrod | Brad Dekker | Major Will Thorpe | 1 | 4 |
| Tymberlee Hill | Julie Taylor | Intern Claire | 1 | 16 |
| Mark Adair-Rios | Mario "Trucho" Mendoza | David Morris | 1 | 6 |
| Alyssa Milano | Kyra Blaine | Haylee Peterson | 1 | 1 |
| Anne Dudek | Emma Carnes | Elise Castor | 1 | 1 |
| Brett Tucker | Detective Inspector Colin Hunt | Lucas Ripley | 1 | 1 |
| Crystal Allen | Ms. Pauline DeGarmo | Heather | 1 | 1 |
| Currie Graham | Stanford Raynes | Greg | 1 | 1 |
| Dawnn Lewis | Yvonne | Jamarah Blake | 1 | 3 |
| Eric Ladin | Daniel Sullivan | Victor Brown | 1 | 1 |
| Eric Lange | Simon Warburg | Steven Tanner | 1 | 1 |
| Ever Carradine | Mirielle Lefcourt | Athena | 1 | 1 |
| Frances Fisher | Matilda King | Betty Johnson | 1 | 1 |
| François Chau | Clifford Lee | Mr. Chue | 1 | 1 |
| Jackie Tohn | Cyber Rita | Lindsay Allyn | 1 | 1 |
| Jamie Chung | Romy Lee | Trina Paiz | 1 | 1 |
| Jen Lilley | Julia Foster | Kara Fisher | 1 | 1 |
| Joelle Carter | Maggie Ingram | Mary | 1 | 1 |
| K Callan | Delores Marsh | Janis | 1 | 1 |
| Kathleen Rose Perkins | Elise Finnegan | Sarah | 1 | 1 |
| Lance Henriksen | Benny Stryker | Griffin McColl | 1 | 1 |
| Lise Simms | Wendy Johnson | Karen | 1 | 1 |
| Michael Hyatt | Mrs. Leslie Ruiz | Mariann Davidson | 1 | 1 |
| Molly Hagan | Daisy May | Jackie | 1 | 1 |
| Rosalind Chao | Mimi Tan | Kathleen Patterson | 1 | 1 |
| Teri Reeves | Miranda Vail | Rory | 1 | 1 |
| Titus Makin, Jr. | Tim Cabot | Rick Schultz | 1 | 1 |
| Vedette Lim | Meadow | Dr. Polly Preston | 1 | 1 |
| Bess Armstrong | Paula Casillas | Maureen Lincoln | 1 | 4 |
| Mac Brandt | Jeremy | Paramedic #3 | 1 | 4 |
| Ryan Devlin | Steven Reed | Bill Portman | 1 | 4 |
| Bill Smitrovich | Ben Davidson | Dr. Walter Carr | 1 | 2 |
| Dean Norris | Captain John Davis | Vince | 1 | 2 |
| Jocko Sims | Matt Hendricks | Randy | 2 | 1 |
| John Billingsley | Dr. Harvey Larson | Jacob Nolston | 1 | 2 |
| Josh Stamberg | Martin Danberg | Tommy Walker | 2 | 1 |
| Kristin Lehman | Serena Kaye | Cora | 1 | 2 |
| Linda Park | Chief Inspector Zhang | Deborah Lee | 1 | 2 |
| Mackenzie Astin | Phillip Bartlett | Danny Wilson | 1 | 2 |
| Patrick Fabian | Peter Monroe | Dr. Oliver Lebackes | 1 | 2 |
| Summer Glau | Kendall Frost | Nurse Emily Kovach | 1 | 2 |
| Tim Griffin | Spalding Elliot | Ronny O'Malley | 1 | 5 |
| Arlene Santana | Jasmine | Nurse | 1 | 10 |
| Kyle Secor | Deputy Director Anthony Freedman | John Dickinson | 1 | 3 |
| Phil Abrams | Roger | Dr. Jim Nelson | 1 | 3 |
| Tom Irwin | Simon Campbell | Officer Hancock | 1 | 3 |
| Troy Winbush | Marcus Ford | Darren Riley | 1 | 3 |
| Michelle Alegria | Reporter / News Anchor | Morning Anchor 'Diane' | 5 | 1 |
| Alex Fernandez | Capt. Marcus Donovan | FBI Agent Heyward | 1 | 2 |
| Alimi Ballard | Frank Jackson | Brent | 1 | 1 |
| Amy Hill | Alma | Joanne | 1 | 1 |
| Anne Ramsay | Bree Busch | Wanda Gallagher | 1 | 1 |
| Anne-Marie Johnson | Sondra Kramer | Judge Madeline Kane | 1 | 1 |
| Bre Blair | Toni Johnston | Lauren Pailey | 1 | 1 |
| Candice Patton | Young Woman | Megan Waylon | 1 | 1 |
| Charlie Hofheimer | Eric Chambers | Jason Castor | 1 | 1 |
| Cullen Douglas | Noah Lewis | Dr. Bob Richardson, Mr. Arnold | 1 | 2 |
| D.B. Woodside | Lance Carlberg | Marcus King | 1 | 1 |
| Danielle Bisutti | Claire Panchard | Liz Langer | 1 | 1 |
| Dave Shalansky | Tech #1 | Jeremy | 1 | 2 |
| David Chisum | Thomas Gage | Judge Jeffrey King | 2 | 1 |
| Derek Phillips | Reggie Walsh | Dale Winick | 1 | 2 |
| Derek Webster | Mayor Robert Weldon | Paul Anderson | 1 | 1 |
| Dohn Norwood | Charles Oni | Lou | 1 | 1 |
| Gilles Marini | Tobias Strange | Michael | 1 | 1 |
| Gregg Henry | Winston Wellesley | Dr. Gracie | 1 | 1 |
| Jacqueline Obradors | Allison Hyde | Valeria Cardenas | 1 | 3 |
| Jayne Brook | Claudia Peterson | Gwen Graber | 1 | 1 |
| Joe Nieves | Boyd Gamble | Michael Baker | 1 | 1 |
| José Zúñiga | Alfredo Quintana | Anthony Meloy | 1 | 1 |
| Josh Randall | Miles Haxton | William | 1 | 1 |
| Judith Hoag | Cynthia Hamilton | Rhada Douglas | 1 | 2 |
| Kevin Christy | Todd / Brandon Northcliff | Brady Sullivan | 1 | 1 |
| Kristen Ariza | Sandra Whitman | Angela | 1 | 1 |
| Larry Sullivan | Samuel Lynchberg | David Young | 1 | 1 |
| Mark Pellegrino | Tom Dempsey | Chris | 1 | 1 |
| Michael Rady | Evan Murphy | Mike Shelley | 1 | 1 |
| Monica Keena | Colleen McCann | Bonnie Crasnoff | 1 | 2 |
| Navi Rawat | Rachel Walters | Heidi | 1 | 1 |
| Omid Abtahi | Waqas Rasheed | Aasif | 1 | 1 |
| Patrick Fischler | Leo | Jake Steiner | 1 | 1 |
| Peter Katona | Keith Murphy | Marcus Kane | 1 | 1 |
| Raphael Sbarge | Dr. Darrell Meeks | Paul | 1 | 2 |
| Robert Pine | Gerry Finnegan | Vincent | 1 | 1 |
| Rodney Rowland | Mick Linden | Brian | 1 | 1 |
| Rose Abdoo | Dr. Cynthia Swann | Dr. Dawson | 1 | 1 |
| Sam Anderson | Principal Duncan | Michael Whitman | 1 | 1 |
| Sarah Jane Morris | Leslie Morgan Thomas | Emily Vaughn | 1 | 1 |
| Scott Michael Campbell | Lee Travis | Mr. Hubble | 1 | 1 |
| Seth Green | Linus | Nick Hanscom | 1 | 2 |
| Shannon Lucio | Rebecca Fog | Amanda | 1 | 3 |
| Stephanie Maura Sanchez | News Anchor | Admitting Nurse | 1 | 1 |
| Tiffany Dupont | Greta Mastroianni | Zoe | 1 | 1 |
| Vanessa Bell Calloway | Beryl Wickfield | Lucinda Gamble | 1 | 2 |
| Wendy Davis | NYFD Lt. Delia Burton | Holly Adams | 1 | 1 |
| Ali Hillis | Megan Brooks | Lori Carter | 1 | 4 |
| Dominic Hoffman | Andrew Spencer | Dr. Jeff Russell | 1 | 4 |
| Billy Mayo | Senior Officer | Rick | 2 | 2 |
| Joyce Guy | Judge Kerry Fallbrook | Ms. Henry | 1 | 3 |
| Bernard White | Anwar El-Masri | Dr. Darwich | 2 | 1 |
| John Getz | Dr. Gustavo Bauer | Michael Breyers | 1 | 2 |
| Kwame Patterson | Wardell Williams | Kwame | 1 | 2 |
| Merrin Dungey | Monica Finch | Dr. Naomi Bennett | 1 | 2 |
| Alexa Havins Bruening | Elle Daniels | Danielle | 1 | 1 |
| Alexandra Barreto | Annie Swift | Pammy | 1 | 1 |
| Alexis Carra | Julie | The Other Woman | 1 | 1 |
| Allan Louis | Capt. Frank Mahoney | Ronald Lace | 1 | 1 |
| Amy Aquino | Janine Marks | Marianne Grandy | 1 | 1 |
| Amy Gumenick | Danielle | Becca Wells | 1 | 1 |
| Camille Chen | Donna Brooks | Kerry Schultz | 1 | 1 |
| Casey Sander | Billy O'Rourke | Casey | 1 | 1 |
| Catherine Dent | Beth Tanner | Cathy Rogerson | 1 | 1 |
| Christopher Carrington | Man | Sam Kenton | 1 | 1 |
| Courtney Ford | Courtney Ford | Jill Meyer | 1 | 1 |
| David Grant Wright | Ben Moss | Mr. Burton | 1 | 1 |
| Drew Powell | Sam Carson | Carl Shatler | 1 | 1 |
| Gary Basaraba | Ralph Carbone | Micah | 1 | 1 |
| George Newbern | Howard Peterson | Stan Mercer | 1 | 1 |
| Graham Beckel | Ted Murphy | Jim Johnson | 1 | 1 |
| Jessica Tuck | Joy McHugh | Shannon's Mom | 1 | 1 |
| Jim Gleason | Dr. Barry Frank | Dr. Domner | 1 | 1 |
| John Allen Nelson | Walter Dennis | Arthur Soltanoff | 1 | 1 |
| Judith Moreland | Sandy Jenkins | Mrs. Baer | 1 | 1 |
| Julie Gonzalo | Madison Queller | Teresa Benson | 1 | 1 |
| June Squibb | Jamie Isaacson | Dr. Elsie Clatch | 1 | 1 |
| Kathe Mazur | Anya Mishkin | Mrs. Epstein | 1 | 1 |
| Kenneth Mitchell | Paul Whittaker | Wade Solomon | 1 | 1 |
| Mark Moses | Blake Wellesley | Dr. Larry Maxwell | 1 | 1 |
| Matthew Alan | Jason Bagwell | David Fisher | 1 | 1 |
| Michael Reilly Burke | Frank Nesbit | Mr. Finch | 1 | 1 |
| Natalie Lander | Marie | Judith Dunn | 1 | 1 |
| Nikki DeLoach | Annie Klein | Charlotte | 1 | 1 |
| Paula Newsome | Debbie Parker | Mrs. Sturgeon | 1 | 1 |
| Perrey Reeves | Helen Parker | Margaret | 1 | 1 |
| Ping Wu | Dr. Lee | Seymour Glass | 1 | 1 |
| Rebeka Montoya | Ana Rivera | Marisela | 1 | 1 |
| Rick Peters | Tony Blaine | Sean Greene | 1 | 1 |
| Romy Rosemont | Nurse Lockhart | Lea Seibert | 1 | 1 |
| Scottie Thompson | Tildy McGuire | Dr. Renee Collier | 1 | 1 |
| Shane Johnson | Deputy Adam Jones | Anthony Valentine | 1 | 1 |
| Spencer Garrett | Evan Pierce | Jim Walker | 1 | 1 |
| Stephanie Faracy | Patty Schultz | Mrs. Sullivan | 1 | 1 |
| Tom Amandes | Aaron Stokes | Charlie Waller | 1 | 1 |
| Wallace Langham | Dr. Van Holtzman | Dr. Steve Corridan | 1 | 1 |
| Wes Ramsey | John Henson | Jimmy | 1 | 1 |
| William Allen Young | Jerry Camden | Morris Haynes | 1 | 1 |
| William R. Moses | Blake Wilder | Steven | 1 | 1 |
| Coby Ryan McLaughlin | Brooks | Chad Anderson | 2 | 1 |
| Jillian Armenante | Susan Mailer | Mindy Carlson | 1 | 2 |
| Laura Coover | Amy Barrett, Susan Watts | Wendy Cole | 2 | 1 |
| Siena Goines | Donna Vincennes | Natasha Deon | 1 | 2 |
| Aasha Davis | Alyssa Lofters | Rina | 1 | 2 |
| Adargiza De Los Santos | Receptionist | Nadine Talbott | 1 | 1 |
| Alan Blumenfeld | Hank Harper | Shawn Sullivan | 1 | 1 |
| Amy Rosoff | Katrina | Kira Donnelly | 1 | 1 |
| Barry Livingston | Abe | Wayne Sheehan | 1 | 1 |
| Bellamy Young | Candace Ford | Kathy | 1 | 2 |
| Brennan Elliott | Jason Cosway | Dave Kristler | 1 | 1 |
| Brian Howe | Aaron Lerner | Robert Fischer | 1 | 1 |
| Brian Letscher | Liam Finch | Mr. Epley | 1 | 1 |
| Charlene Amoia | Ana Marie | Dr. Kate Lachman | 1 | 1 |
| Dale Waddington Horowitz | Kelly Gunther | OB Resident | 1 | 2 |
| David Burke | Chief John Brady | Don | 1 | 1 |
| Deborah Strang | Ruby | Ellie Ratigan | 1 | 1 |
| Glenn Morshower | Defense Secretary Michael Reed | Walter | 1 | 1 |
| Gregg Daniel | Walt Shaw | Paul James | 1 | 1 |
| Heather Mazur | Gwen Kelly | Erin Mason | 1 | 1 |
| Heather McComb | Nicole Morris | Rachel Burke | 1 | 1 |
| Jackson Hurst | Harlan Mathis | Thomas Archibald | 1 | 1 |
| Jae Jung | Receptionist | Daycare Worker Tara | 1 | 2 |
| Jason Antoon | Steve Warner | Mr. Samuels | 1 | 1 |
| Jeanette Brox | Ayyana Holder | Shelley | 1 | 1 |
| Jeff Doucette | Super | Warren Sterman | 1 | 2 |
| June Carryl | Therapist | Nurse | 1 | 1 |
| Kari Coleman | Julia Hammond | Mother | 1 | 1 |
| Katie Lowes | Rachel Maddox | Blood Donor | 1 | 1 |
| Laura Niemi | Bernie Cosetti | Cynthia | 1 | 1 |
| Lilli Birdsell | Samantha Williger | Emily Rochester | 1 | 1 |
| Lisa Kaminir | Captain Edmunds | Doris Friedman | 1 | 1 |
| Lisa Waltz | Laurie Horn | Margot Billings | 1 | 1 |
| Lori Alan | Ms. Papen | Ellen Weaver | 1 | 1 |
| Mandy June Turpin | Lee Travis' Sister | Karla | 1 | 1 |
| Mark Bloom | Neal Morris | Prosecutor | 1 | 1 |
| Marlene Forte | Blanca | Carmen Delgado | 1 | 2 |
| Matt Pascua | Carlos Villegas | Jess | 1 | 1 |
| Matt Winston | Evan Hinkle | Frank Jeffries | 1 | 1 |
| Mekenna Melvin | Talia McTeague | Katie | 1 | 1 |
| Melinda Page Hamilton | Diana Harris | Dr. Jennifer Stanley | 1 | 1 |
| Michael Bowen | Sergeant Joseph Ortiz | Roy Davis | 1 | 1 |
| Nicole J. Butler | Cassandra | Jess | 1 | 1 |
| Patrick O'Connor | Chris Markum | Judge Finch | 1 | 1 |
| Rachel Boston | Penny Marchand | Rachel | 1 | 1 |
| Rob Nagle | Kirby Smith | Howard Bonaman | 1 | 1 |
| Ron Roggé | Wolkowski | Fire Captain | 1 | 1 |
| Samantha Quan | Kathleen Park | Shelly Boden | 1 | 1 |
| Sandra Thigpen | Mrs. Kirby | Clara | 1 | 1 |
| Scott Allen Rinker | David Anderson | Toby | 1 | 1 |
| Sonya Leslie | Valerie Thompson | Rita | 1 | 1 |
| Sophina Brown | Brooke Carver | Joyce | 1 | 1 |
| Stacy Edwards | Jessica Banks | Kathleen Wheeler | 1 | 1 |
| Wendy Braun | Carol Jarvis | Captain LeVantine | 1 | 1 |
| David Paluck | FBI Agent Michael Glassman | Surgeon #2 | 1 | 2 |
| Anna Grace Barlow | Annie Beakman | Charlotte Marsh | 1 | 1 |
| Austin Highsmith Garces | Camille Roberts | Amber Courier | 1 | 1 |
| Bess Rous | Natalie Barnes | Nina Sullivan | 1 | 1 |
| Brian Poth | Oscar Von Eckland | Keith | 1 | 1 |
| Carolyn Ratteray | Waitress | OB Fellow | 1 | 1 |
| Charlie Bodin | Julian Cutter | Todd | 1 | 1 |
| Chryssie Whitehead | Kathy Moore | Helena Boye | 1 | 1 |
| Daniel Steven Gonzalez | Bronx PD Officer | Paramedic Garza | 1 | 1 |
| David Ramsey | Jim Wheeler | Jimmy Thompson | 1 | 1 |
| David Shatraw | Brian Whitman | Lawyer #2 | 1 | 1 |
| Daya Vaidya | Sophia Del Cordova | Paola Bright | 1 | 1 |
| Don McManus | Archie "The Savannah Hammer" Bronstein | Samuel Linden | 1 | 1 |
| Drew Rausch | Officer Ted Lane | John Finch | 1 | 1 |
| Emil Beheshti | Dean Seahorn | Man with Plaid Bow Tie | 1 | 1 |
| Erin Way | Audrey O'Neill | Donna Woods | 1 | 1 |
| Gina Hecht | Marie Russo | Mrs. Sutton | 1 | 1 |
| Greg Cromer | Harvey Stryker | Dana | 1 | 1 |
| Idara Victor | Patty | Amelie Ward | 1 | 1 |
| Isaiah Mustafa | Team Leader | Brian Williams | 1 | 1 |
| Janet Song | Nurse | Desk Worker | 1 | 1 |
| John M. Jackson | Rod Halstead | Kevin Covington | 1 | 1 |
| Jon Curry | Stan Kopek | Fred Fisher | 1 | 1 |
| Joshua Wolf Coleman | Reporter #2 | Lawyer | 1 | 1 |
| Judyann Elder | Melinda Parish | Angelica Paulson | 1 | 1 |
| Kathleen Mary Carthy | Lorraine Dinovi | Mrs. Miller | 1 | 1 |
| Lex Medlin | Seth Parrino | Byron Gibbis | 1 | 1 |
| Linara Washington | Christina Marx | Gretchen McKay | 1 | 1 |
| Michael McGrady | Brian Reilly | Stanley Singer | 1 | 1 |
| Ned Vaughn | Brett Zaretsky | Representative for the Airline | 1 | 1 |
| Ramón de Ocampo | Owen Peterson | James Benton | 1 | 1 |
| Richard Portnow | Detective Milt Boyle | Saul | 1 | 1 |
| Romi Dias | ADA Toni Gonzalez | Nadi Correa | 1 | 1 |
| Sam Daly | Jack Hastings | Will Jones | 1 | 1 |
| Scott Cohen | Lt. Stan Holliwell | Dr. Tom Evans | 1 | 1 |
| Scott Michael Morgan | Sam Mackey | Patient #2 | 1 | 1 |
| Susan Ruttan | Eleanor Pike | Mrs. Swore | 1 | 1 |
| Suzy Nakamura | Jennifer Wong | Jenn Smith | 1 | 1 |
| T.J. Ramini | Prince Khalid Hasheim | Mr. Al-Hasan | 1 | 1 |
| Todd Waring | Doug Ellers | Tobin | 1 | 1 |
| Vanessa Martinez | Lara Blanco | Gretchen Price | 1 | 1 |
| Zoë Hall | Emily Hopper | Risa Hodges | 1 | 1 |
| James McAndrew | Nick Buckley | Nate | 1 | 2 |
| Regi Davis | Dr. Bailey | Dr. Kevin Fisher | 1 | 2 |
| Alexie Gilmore | Anita Miller | Sarah Freemont | 1 | 1 |
| Amy Stewart | Brandy Rossi | Diane Early | 1 | 1 |
| Andrew Borba | Mr. Mudge | Chris Ward | 1 | 1 |
| Antonio Leon | Stinson | Detective Mitch Proust | 1 | 1 |
| Assaf Cohen | Dr. Rusham Haroun | Aamir Elshami | 1 | 1 |
| Benjamin Patterson | Paramedic | Curtis Warren | 1 | 1 |
| Brady Smith | Greg Murphy | Mike Purdy | 1 | 1 |
| Brian Michael Jones | Ty Page | Fish Man | 1 | 1 |
| Chet Grissom | Agent Gray | Uncle Pat | 1 | 1 |
| Clare Carey | Noreen Hixton | Nikki Gibson | 1 | 1 |
| Dahlia Salem | Tory Westchester | Jan Taylor | 1 | 1 |
| Doug Simpson | Henry Browning | Phil Leggett | 1 | 1 |
| Dustin Ingram | Chad | Bruce Fuller | 1 | 1 |
| Elizabeth Ho | Amy Saunders | Molly | 1 | 1 |
| Erin Cahill | Cecily Burkett | Meg Shelley | 1 | 1 |
| Fareed Ward | Bartender | Captain Bruno | 1 | 1 |
| Jesse Head | Zack Metzger | Will | 1 | 1 |
| Jim Turner | Janacek Spivey | Dr. Schacter | 1 | 1 |
| Kai Lennox | Simon | Speed | 1 | 1 |
| Karl T. Wright | Dr. Chuck Vaughn | Divorce Mediator | 1 | 1 |
| Kevin Will | Grant Gerber | Len Gantry | 1 | 1 |
| Larry Clarke | Tony Muller | Paul | 1 | 1 |
| Mark Harelik | Pete Benton | Keith Polus | 1 | 1 |
| Matthew Jaeger | George Keller | Kyle Kasliner | 1 | 1 |
| Maura Soden | Mrs. Faris | Librarian | 1 | 1 |
| Michelle C. Bonilla | Maxine Collins | Dr. Elena Chavez | 1 | 1 |
| Nadji Jeter | Joey Malone | Bobby | 1 | 1 |
| Nick Jaine | Forensic IT Guy | Tim | 1 | 1 |
| Paul Zies | Frankie | Biker Dude | 1 | 1 |
| Peter MacKenzie | Sgt. Roman | Warren Kramer | 1 | 1 |
| Rob Brownstein | Captain Ziering | Larry | 1 | 1 |
| Sarah Lilly | Luella McManus | Joyce Basche | 1 | 2 |
| Ursula Burton | Ms. Cooper | E.R. Nurse | 1 | 2 |
| Walter Perez | Bobby Lopez | Russ | 1 | 1 |
| Adam Kulbersh | Brian Shay | Tommy | 1 | 1 |
| Albie Selznick | Dr. Paul Devlin | Columbia Representative | 1 | 1 |
| Aly Mawji | Evan | Dr. Russell | 1 | 1 |
| Benjamin Ciaramello | Vin | Darren Covington | 1 | 1 |
| Brian Maillard | Joel Mitas | Perfusionist | 1 | 1 |
| Christie Lynn Smith | Melanie Kopek | Cynthia Daniels | 1 | 1 |
| David Bowe | Max Haverstock | Don | 1 | 1 |
| Gil McKinney | Tyler Benton | Chris | 1 | 1 |
| Gwendoline Yeo | Elise Kim | Michelle Carpio | 1 | 1 |
| Jeff Davis | Dave Johnson | Recruiting Officer | 1 | 1 |
| Jonathan Slavin | Justin Hankel | Rick Beglighter | 1 | 1 |
| Julio Oscar Mechoso | Mario Sanchez | Chucky Eaton | 1 | 1 |
| Kareem Grimes | Omar Lincoln | Steve | 1 | 1 |
| Kate Cobb | Gwen Parker | Mari Prishna | 1 | 1 |
| Kyla-Drew Simmons | Sophie | Mia James | 1 | 1 |
| Lak Rana | Tech #3 | N.D. Peds Surgeon | 1 | 1 |
| Mapuana Makia | Tech | Casey Lee | 1 | 1 |
| Mason McCulley | Percy Johnson III | Ryan | 1 | 1 |
| Matt Roth | Philip Dagmar | Michael Beglighter | 1 | 1 |
| Michanne Quinney | Trainee | Tori | 1 | 1 |
| Nancy La Scala | Colette Robinson | Lucia | 1 | 1 |
| Peggy Dunne | Mrs. Heller | Louise | 1 | 1 |
| Rick Worthy | Jason Penn | Ray Pelletier | 1 | 1 |
| Ron Melendez | Jeff Dilahunt | Will Sales | 1 | 1 |
| Ronnie Alvarez | Juan | Barista | 1 | 1 |
| Roshawn Franklin | Derek 'Lightning' Bolt | Todd Holmes | 1 | 1 |
| Shelli Boone | Chantal | Paula Glass | 1 | 1 |
| Stephen Oyoung | Guard | Greg Zheng | 1 | 1 |
| Tyrees Allen | Harvey Milton | Dr. Saltzman | 1 | 1 |
| Jennifer Jean Snyder | Anchor, Reporter | Reporter | 2 | 1 |
| Ajay Vidure | CSU tech | Intern #1 | 1 | 1 |
| Amy Tolsky | Sue Williams | Tonya Orvis | 1 | 1 |
| Brian Scolaro | Dave Barton | Mike | 1 | 1 |
| Cal Gibson | Chess Player | Larry Keys | 1 | 1 |
| Colby French | NYPD Detective | Mr. Filson | 1 | 1 |
| Denise Dowse | Judge Gloria Wollcott | Lorraine | 1 | 1 |
| Eamon Hunt | Frank Garrison | Judge Brentner | 1 | 1 |
| George Gerdes | Michael Yanavich | Norman Sholman | 1 | 1 |
| James Huang | Edward Han | Social Worker | 1 | 1 |
| Jason Kelley | Event Organizer | Chuck | 1 | 1 |
| Jeris Lee Poindexter | Older Man | Mr. Strickland | 1 | 1 |
| John Hemphill | Tom Walters | Brad Nystrom | 1 | 1 |
| John Paul Pitoc | Darius Langley | Billy Sheehan | 1 | 1 |
| Josh Daugherty | Trent Wellesley | Ken Daniels | 1 | 1 |
| Marcus Choi | EMT | Young Man | 1 | 1 |
| Mark Berry | Captain Bigelow | AA Member | 1 | 1 |
| Matt McTighe | Chuck Ryker | Vincent Wagner | 1 | 1 |
| Matthew Carey | Mr. Levine | Will | 1 | 1 |
| Pamela Shaddock | Marcella | Shara Freeman | 1 | 1 |
| Paul Cassell | Marcus Conway | John Hanson | 1 | 1 |
| Scott Klace | Wallace Williger | Dr. Jordan Wagner | 1 | 1 |
| Tim De Zarn | Bartender | Santa Claus | 1 | 1 |
| Wilmer Calderon | Marvin "Oz" Osminkowski | Raul Aranda | 1 | 1 |
| Brian Oblak | Head of Security | Daniel Rudin | 1 | 1 |
| Carlease Burke | Storage manager | Mrs. Gates | 1 | 1 |
| Christopher Michael | Officer Simms | Ray | 1 | 1 |
| Corey Mendell Parker | Reggie Dyson | Brian Wilson | 1 | 1 |
| Eileen Fogarty | Élodie | Mrs. Chen's Sister | 1 | 1 |
| Emily Davenport | Abby Smith | Monica Zarr | 1 | 1 |
| Gerald Downey | Lloyd Kurtzman | Dr. Kenton Giles | 1 | 1 |
| Hahn Cho | Hazmat Specialist | Dr. Dale Wong | 1 | 1 |
| Houston Rhines | Stephen Addison | Boy | 1 | 1 |
| Jaime Alvarez | Cal Harper | Suited Man | 1 | 1 |
| Jeremy Glazer | Nick Keller | Drew Hawkins | 1 | 1 |
| Jerry Kernion | Albert Bolland | Bobby Corso | 1 | 1 |
| Kasey Mahaffy | Lance Newman | Billy Best | 1 | 1 |
| Kate Rene Gleason | Officer | Elyse Cruse | 1 | 1 |
| Liz Benoit | Assistant | Woman | 1 | 1 |
| Meg Cionni | Tessa | Nikki Jones | 1 | 1 |
| Michael Duisenberg | Bodyguard | Policeman | 1 | 1 |
| Monica Garcia | Cleaning Lady | Peds Nurse | 1 | 1 |
| Paul Terrell Clayton | Dax Lattimer | Mr. Donovan | 1 | 1 |
| Ruben Dario | EMT | Brad Gailis | 1 | 1 |
| Sam Ayers | Bartender | Detective | 1 | 1 |
| Vivian Kerr | Amanda Lowery | Logger's Wife | 1 | 1 |
| Ayanna Berkshire | Interviewer | Surgeon #1 | 1 | 1 |
| Bruce Katzman | Benjamin Morris | Wayne Sheehan | 1 | 1 |
| Cantrell Harris | Officer Ellroy | Rescue Worker | 1 | 1 |
| Hilary Ward | Bella | Dr. Thompson | 1 | 1 |
| John Gloria | Bartender | Rob Kane | 1 | 1 |
| Ken Meseroll | Man | Ron | 1 | 1 |
| Mike Faiola | Paul Morton | Guy | 1 | 1 |
| Nina Rausch | Receptionist | Sheila Davis | 1 | 1 |
| Steven M. Gagnon | Colonel Fortis | Mr. Lepik | 1 | 1 |
| Susan Grace | Carla | Jane | 1 | 1 |
| Taneka Johnson | Edwina | Nurse Khadijah | 1 | 1 |
| Charles Carpenter | Reporter | Party Guy #1 | 1 | 1 |
| Chase Kim | FBI Specialist | Lawyer | 1 | 1 |
| Ingrid Walters | Publicist | Nurse Vivian | 1 | 1 |
| Michael Petrone | Ivan | Carl Holcomb | 1 | 1 |
| Michelle N. Carter | Woman | Exam Proctor | 1 | 1 |
| Nick Hoffa | Staff Sgt. Cass | Firefighter #2 | 1 | 1 |
| Sarah Butler | Whitney Williams | Danielle | 1 | 1 |
| Anita Finlay | Margo Falcigno | Lady Donor | 1 | 1 |
| Arianna Ortiz | Librarian | Jessica Schoman | 1 | 1 |
| Jarrod Crawford | Field Tech | Dr. Oslow | 1 | 1 |
| Jaye Razor | Security Guard | Rage | 1 | 1 |
| Marin Hinkle | Dr. Rebecca Ellins | Ashley Cordova | 1 | 1 |
| Yolanda Snowball | Rebecca Doolin | Physical Therapist | 1 | 1 |
| Artie O'Daly | Building Manager | Intern #3 | 1 | 1 |
| Bob Bancroft | Mitch Greenberg | Leonard Olsen | 1 | 1 |
| Brett Rickaby | Robert McManus | Mr. Weston | 1 | 1 |
| Edelyn Okano | Bree Colton | Nurse | 1 | 1 |
| Herbie Jackson | Bobby Jones | Adam | 1 | 1 |
| Darren Dupree Washington | Security Aide | Reporter | 1 | 1 |
| Dave Florek | Harvey | Herman Crum | 1 | 1 |
| Josh Fingerhut | Worker | Police Officer | 1 | 1 |
| Matt Kaminsky | Evan Howard | Rashy Man | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.