All 52 actors in both Castle and The Big Bang Theory
52 actors have appeared in both Castle and The Big Bang Theory, across 452 episodes. The most-credited is Casey Sander, Billy O'Rourke in Castle and Mike Rostenkowski in The Big Bang Theory.
| Actor | In Castle | In The Big Bang Theory | Eps | Eps |
|---|---|---|---|---|
| Casey Sander | Billy O'Rourke | Mike Rostenkowski | 1 | 6 |
| Dean Norris | Captain John Davis | Colonel Williams | 1 | 6 |
| Mark Harelik | Pete Benton | Dr. Eric Gablehauser | 1 | 5 |
| Vernée Watson | Mercy LaGrande | Althea | 1 | 5 |
| Michael Trucco | Detective Tom Demming | Dr. David Underhill | 4 | 1 |
| Valerie Azlynn | Officer Ann Hastings | Alicia | 3 | 1 |
| Dakin Matthews | David Dunne | Santa | 1 | 2 |
| Beth Behrs | Ginger | Nell | 1 | 1 |
| Jim Turner | Janacek Spivey | Reverend White | 1 | 1 |
| Jodi Lyn O'Keefe | Kristina Coterra | Mikayla | 1 | 1 |
| Julio Oscar Mechoso | Mario Sanchez | Officer Hackett | 1 | 1 |
| Michael Hyatt | Mrs. Leslie Ruiz | Charlotte | 1 | 1 |
| Summer Glau | Kendall Frost | Summer Glau | 1 | 1 |
| Tate Ellington | Henry Wright | Mitchell | 1 | 1 |
| Elena Campbell-Martinez | Mama | Maria | 1 | 2 |
| Jim Meskimen | Randolph Addison | Doctor, Man, Minister | 1 | 2 |
| Oliver Muirhead | Bryce Robert, Steven Heisler | Professor Laughlin | 2 | 1 |
| Artie O'Daly | Building Manager | Young Man | 1 | 1 |
| Eric Nenninger | John Dessens | Neil | 1 | 1 |
| Jim Holmes | Dr. Ian Fuller | Tim | 1 | 1 |
| Judith Moreland | Sandy Jenkins | Jan | 1 | 1 |
| June Squibb | Jamie Isaacson | Meemaw | 1 | 1 |
| Malcolm Foster Smith | Officer Haskell | Roy | 1 | 1 |
| Tiffany Dupont | Greta Mastroianni | Angela | 1 | 1 |
| Troy Winbush | Marcus Ford | Paramedic | 1 | 1 |
| Angela Relucio | Paramedic | Hostess | 1 | 1 |
| Christine Corpuz | Receptionist | Woman | 1 | 1 |
| Courtney Ford | Courtney Ford | Alice | 1 | 1 |
| Creagen Dow | Max Heller | Maitre D'hôtel | 1 | 1 |
| David Barrera | Principal Joe Silva | Officer Hernandez | 1 | 1 |
| Eddie Shin | Johnny Vong | Dr. Park | 1 | 1 |
| Ian Reed Kesler | Hugo Morrison | Paramedic #2 | 1 | 1 |
| Karl T. Wright | Dr. Chuck Vaughn | Jimmy | 1 | 1 |
| Katherine Von Till | Janice Elden | Tech Support Recording | 1 | 1 |
| Ken Lerner | NYPD Attorney | Dr. Schneider | 1 | 1 |
| Lanny Joon | Philip Lee | Officer Shin | 1 | 1 |
| Michael Dempsey | Frank Malloy | Security Guard | 1 | 1 |
| Peter Onorati | Sal Malavolta | Angelo | 1 | 1 |
| Phil Abrams | Roger | Dr. Bernstein | 1 | 1 |
| Riccardo Lebron | Orlando Costas | Tom | 1 | 1 |
| Seth Coltan | Maintenance Worker | Earl | 1 | 1 |
| Stephanie Escajeda | Tourist | Cindy | 1 | 1 |
| Claudia Choi | CSU Photo Technician, Video Technician | Woman #3 | 2 | 1 |
| Dinora Walcott | Det. Mindy Stegner | Reporter #1 | 1 | 1 |
| Mark Berry | Captain Bigelow | Pit Boss | 1 | 1 |
| Monica Garcia | Cleaning Lady | Maria | 1 | 1 |
| Nicole J. Butler | Cassandra | Clerk | 1 | 1 |
| Will Deutsch | Nerdy Guy | Jeremy | 1 | 1 |
| Amy Tolsky | Sue Williams | Joan | 1 | 1 |
| Craig Gellis | Earl Moreland | Car Thief #1 | 1 | 1 |
| Rodney J. Hobbs | Worker | Reporter #3 | 1 | 1 |
| Endre Hules | Pavel Oborin | Russian Mission Control | 1 | 1 |
← Castle × The Big Bang Theory
Cast data from TVmaze, licensed CC BY-SA 4.0.