All 72 actors in both Chuck and Grey's Anatomy
72 actors have appeared in both Chuck and Grey's Anatomy, across 558 episodes. The most-credited is Mekenna Melvin, Alex McHugh in Chuck and Katie in Grey's Anatomy.
| Actor | In Chuck | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Mekenna Melvin | Alex McHugh | Katie | 24 | 1 |
| Julia Ling | Anna Melinda Wu | Emma | 8 | 1 |
| John O'Brien | Older Technician | Lab Tech Jeffrey | 1 | 13 |
| Eric Roberts | Kyle Packard | Dr. Robert Avery | 1 | 2 |
| Jonathan Cake | Agent Cole Barker | Griffin Ford | 2 | 1 |
| Clare Carey | Kathleen McHugh | Nikki Gibson | 4 | 1 |
| Jack Yang | Jason Wang | Walter | 1 | 4 |
| Isaiah Mustafa | Greta #2 | Brian Williams | 2 | 1 |
| Phil Abrams | Stanford Librarian | Dr. Jim Nelson | 1 | 3 |
| Martin Yu | Engineer #2 | Anesthesiologist, Resident, CT Tech | 1 | 6 |
| Alex Fernandez | Commandante Juan Pablo Turrini | FBI Agent Heyward | 1 | 2 |
| Carl Lumbly | Ty Bennett | Kurt Walling | 1 | 1 |
| David Burke | Mr. Mercer | Don | 3 | 1 |
| Eric Lange | Colin Davis | Steven Tanner | 1 | 1 |
| Gwendoline Yeo | Mei-Ling Cho | Michelle Carpio | 1 | 1 |
| Michael Lesly | Armed Guard | Flight Paramedic | 1 | 3 |
| Robert Picardo | Dr. Howard Busgang | Mr. Nelligan | 1 | 2 |
| Summer Glau | Greta #4 | Nurse Emily Kovach | 1 | 2 |
| Mark Pellegrino | Alexander Winterborne | Chris | 2 | 1 |
| Allan Louis | Dr. Martin Kowambe | Ronald Lace | 1 | 1 |
| Anthony Azizi | Sheik Rajiv Amad | Syrian Doctor | 1 | 1 |
| Erin Cahill | Bobbi | Meg Shelley | 1 | 1 |
| François Chau | Guillermo Chan | Mr. Chue | 1 | 1 |
| Larry Cedar | Interviewer | Dr. Cohn | 1 | 1 |
| David Paluck | Ship's Manager | Surgeon #2 | 1 | 2 |
| Melvin Abston | Attendant | Cop | 1 | 2 |
| Treisa Gary | Wife, Woman | Beth | 2 | 1 |
| David Goryl | Bank Security Guard | Ron Campion | 1 | 1 |
| Emy Coligado | Poppy Tang | Janelle Duco | 1 | 1 |
| Faran Tahir | Farrokh Bulsara | Isaac | 1 | 1 |
| Jadin Gould | Young Ellie | Ivy McNeil | 1 | 4 |
| Kim Swennen | Denise | Kelly | 1 | 1 |
| Mo Collins | Colonel Caroline Hayne | Jessica's Mom | 1 | 1 |
| Tom Choi | Skinny Guard | Flouroscope Tech | 1 | 1 |
| Vincent Duvall | Duncan | Rick Henry | 1 | 1 |
| Aaron Lustig | Government Scientist | Judge William Benson | 1 | 1 |
| Artie O'Daly | Bell Man | Intern #3 | 1 | 1 |
| Catherine Dent | Jane Robertson | Cathy Rogerson | 1 | 1 |
| Ian Jensen | Scotty | Phillip Nichols | 1 | 1 |
| James Francis Ginty | Lewis | Dr. Russell | 1 | 1 |
| Jason Kelley | Piano Player | Chuck | 1 | 1 |
| Mary Pat Gleason | Morgue Technician | Marge Walker | 1 | 1 |
| Matt Winston | Barclay | Frank Jeffries | 1 | 1 |
| Michael Weaver | Dick Duffy | Greg | 1 | 1 |
| Michelle N. Carter | Bank Teller | Exam Proctor | 1 | 1 |
| Tim Chiou | Mighty Jock | Paramedic #6 | 1 | 3 |
| Yutaka Takeuchi | Business Woman | Kamaji | 1 | 1 |
| Ewan Chung | Lee Cho | Tech Guy | 1 | 1 |
| Frank Krueger | CIA Agent | Dean | 1 | 1 |
| Matt Roth | Buy More Employee | Michael Beglighter | 1 | 1 |
| Michael Hagiwara | Therapist | Charles Hyatt | 1 | 1 |
| Pamela Roylance | Sarah's Grandmother | Alice Bickham | 1 | 1 |
| Rubén Garfias | Juan | Bob | 1 | 1 |
| Sara Van Horn | Elderly Woman | Nash's Grandma | 1 | 1 |
| Sinqua Walls | Student | Tom Kates | 1 | 1 |
| Steve Monroe | Irv | Orderly | 1 | 1 |
| Tina Huang | Maureen Mitsubushi | Roxanne | 1 | 1 |
| Craig Susser | DeLorean Owner | Dr. Hurst | 1 | 1 |
| Kelvin Han Yee | Rashan Chen | Dr. James Lew | 1 | 1 |
| Lori Alan | Judy Roberts | Ellen Weaver | 1 | 1 |
| Mandy Levin | Woman | Dana Leggett | 1 | 1 |
| Sterling Jones | Alex Coburn | Peter Martin | 1 | 1 |
| Alexis Raich | Suzie O'Keefe | Tara Brown | 1 | 1 |
| Brandon Ford Green | Conscientious Customer | Dr. Allen | 1 | 1 |
| Graham Clarke | Englishman | Weather Guy 'Len' | 1 | 1 |
| Ping Wu | Mr. Wu | Seymour Glass | 1 | 1 |
| Sean C. Graham | Husband | Baby's Dad | 1 | 1 |
| Carolyn Power | Nurse | Victoria | 1 | 1 |
| Maurice Whitfield | Guard A.K.A. Terrence | Police Officer | 1 | 1 |
| Maz Siam | Souad Al Habi | Emir's Chief of Staff | 1 | 1 |
| Yolanda Snowball | Justice of the Peace | Physical Therapist | 1 | 1 |
| Philip Shahbaz | Art Dealer | Arab Translator | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.