All 226 actors in both CSI: Crime Scene Investigation and The X-Files
226 actors have appeared in both CSI: Crime Scene Investigation and The X-Files, across 555 episodes. The most-credited is Mitch Pileggi, Happy Harry Desmond in CSI: Crime Scene Investigation and Assistant Director Walter Skinner in The X-Files.
| Actor | In CSI: Crime Scene Investigation | In The X-Files | Eps | Eps |
|---|---|---|---|---|
| Mitch Pileggi | Happy Harry Desmond | Assistant Director Walter Skinner | 1 | 70 |
| Alex Carter | Detective Vartann | Chief Strong | 39 | 1 |
| Nicholas Lea | Chris Bezich | Agent Alex Krycek, Michael | 4 | 25 |
| Annabeth Gish | Laura Gabriel | Special Agent Monica Reyes | 3 | 7 |
| Scott Wilson | Sam Braun | Reverend Orison | 8 | 1 |
| Cary Elwes | Police Officer | Assistant Director Brad Follmer | 1 | 6 |
| Xander Berkeley | Sheriff Rory Atwater | Dr. Hodge | 5 | 1 |
| Doug Hutchison | Dalton Betton, Nigel Crane | Eugene Victor Tooms | 3 | 2 |
| Conor O'Farrell | Undersheriff McKeen | Sheriff Ciolino | 13 | 1 |
| Glenn Morshower | Sheriff Brian Mobley | Aaron Starkey | 7 | 1 |
| Nick Chinlund | Gus Davis, Mickey Rutledge | Donald Eddie Pfaster | 2 | 2 |
| Titus Welliver | Mark Gabriel | Doug Spinney | 3 | 1 |
| Judith Scott | Dr. Jenna Williams | Dr. Kai Bowe | 6 | 1 |
| Raymond J. Barry | Arvin Thorpe, Philip Gerard | Senator Richard Matheson | 4 | 3 |
| Arye Gross | Paul Winston, Vincent DeMarcus | Dr. Puvogel | 2 | 1 |
| Brent Sexton | Mark Doyle | Gravedigger, Steven Melnick | 1 | 2 |
| Eric Nenninger | Jesse, Officer Collins | Jared Chirp | 2 | 1 |
| Jack McGee | Richard O'Malley, Road manager | Bob Damphouse | 2 | 1 |
| Lindsey Ginter | Mr. Daniels | Crew-Cut Man | 1 | 2 |
| Mark Pellegrino | Bruno Curtis, Elliot Perolta | Derwood Spinks | 2 | 1 |
| Mark Sheppard | Dimitri Sadesky, Rod Darling | Bob the Caretaker / Cecil L'Ively | 2 | 1 |
| Michael Bowen | Jason Richter, Marty Cooperman | Dwight Cooper | 2 | 1 |
| Rodney Rowland | Gavin Pallard, Teddy Jr. | Ed Jerse | 2 | 1 |
| W. Earl Brown | Slick, Thomas Pickens | Robert M. Fassl | 2 | 1 |
| Willie Garson | Bud Simmons / Sexy Kitty | Henry Weems, Quinton 'Roach' Freely | 1 | 2 |
| Melinda McGraw | Mrs. Griffin | Melissa Scully | 1 | 4 |
| Timothy Carhart | Eddie Willows | Virgil Incanto | 4 | 1 |
| Aaron Paul | Peter Hutchins Jr. | Winky | 1 | 1 |
| Dean Norris | Phil Baker | U.S. Marshal Tapia | 3 | 1 |
| Don Swayze | Dave Bohr | Terry Pruit | 1 | 1 |
| Fredric Lehne | Curt Ritten, Frank Carrow | Arthur Dales | 2 | 2 |
| Heather McComb | Tara Matthews | Shannon Ausbury | 1 | 1 |
| Jay Acovone | Tommy Grazetti | Duffy Haskell, Det. Joe Curtis | 1 | 3 |
| John Hawkes | Terry Wicker | Phillip Padgett | 1 | 1 |
| Lilyan Chauvin | Mrs. Aloyna Ivanovna | Golda | 1 | 1 |
| Lisa Waltz | Jean Kingsley | Lauren Kyte | 1 | 1 |
| Maggie Wheeler | Female Comic | Detective Sharon Lazard | 1 | 1 |
| Paul McCrane | Phil Carpenter | Leonard Betts | 1 | 1 |
| Pruitt Taylor Vince | Marty Gleason | Gerry Schnauz | 1 | 1 |
| Robert LaSardo | Emilio Alvarado | Cissy Alvarez | 1 | 1 |
| Stacy Haiduk | Gina Sinclair | Maggie Waterston | 1 | 1 |
| Susanna Thompson | Janice Cooper | Michelle Generoo | 1 | 1 |
| Ty Upshaw | Police Officer | Officer #1 | 5 | 1 |
| Vernée Watson | Manager | Nurse Whitney Edwards | 1 | 1 |
| Željko Ivanek | Melton | Roland Fuller | 1 | 1 |
| Michael Bryan French | Dr. Franks, Dr. Stewart | Paul Mossinger | 6 | 1 |
| John Pyper-Ferguson | Dr. William Byrne, Mr. Mandalay | Det. John Kresge, Paul | 2 | 3 |
| Tom Gallop | Attorney Randy Painter | Win Shroeder | 4 | 1 |
| Brian Markinson | Julius Kaplan | Gary Lambert, Tony Fiore | 1 | 2 |
| Garret Dillahunt | Luke, Tom O'Neill | Edward Skur | 2 | 1 |
| Mark Rolston | Sheriff | Bud LaPierre, Richard Odin | 1 | 2 |
| Michael Welch | Steuben Lorenz, Todd Branson | Trevor | 2 | 1 |
| Nestor Serrano | Detective Ortega | Ken Naciamento | 2 | 1 |
| Patrick Kilpatrick | Cesar Dabo, Gary Lee Walt | Randall Cooper | 2 | 1 |
| Patrick St. Esprit | Sheriff Owen Gardner | Guard #2 | 1 | 2 |
| Raymond Cruz | Donald Balboa, Miguel Delgado | Eladio Buente | 2 | 1 |
| Steve Ryan | Sergeant Adams | Sheriff Jack Coogan | 2 | 1 |
| Tamara Clatterbuck | Michelle Acheson, Sandra Hillman | Larina Jackson | 2 | 1 |
| Tracy Middendorf | Belinda Martin, Bridget Willis | Gracie | 2 | 1 |
| Kirk B.R. Woller | Prison Official | Agent Gene Crane | 1 | 5 |
| Allison Smith | Mrs. Diorio, Nancy Linden | Patti | 2 | 1 |
| Alyson Reed | Doris, Mrs. Devereaux | Maggie Lupone | 2 | 1 |
| Benito Martinez | Gabriel Ortiz | Orderly | 1 | 1 |
| Bruce Weitz | Leon Slocomb | Agent Moe Bocks | 1 | 1 |
| Channon Roe | Douglas Granger, Lenny "Moondog" Vanders | Derek Banks | 2 | 1 |
| Chris Ellis | Warden Clinton Malton | Sheriff Lance Hindt | 1 | 1 |
| Clayton Rohner | Park Ranger | Daryl Mootz | 1 | 1 |
| Colby French | Officer Davis | Deputy | 2 | 1 |
| Darren E. Burrows | Mr. Jim Hilliard | Bernard | 1 | 1 |
| Debra Christofferson | Regina Owens | Pat Verlander | 1 | 1 |
| Doug Savant | Paul Brady | Augustus Goldman | 1 | 1 |
| Ed Lauter | Clay Tobin | Colonel Marcus Aurelius Belt | 1 | 1 |
| Frank Novak | Judge | Raybert Fellowes | 2 | 1 |
| Harriet Sansom Harris | Eva | Dr. Sally Kendrick, Eve 6 | 1 | 1 |
| Jeff Kober | Roger Wilder, Walter Douglas Hicks | Bear | 2 | 1 |
| Jere Burns | Dr. Shaw | Dr. Randolph Luvenis | 1 | 1 |
| John Mese | Gordon Wallace | Sheriff Phil Adderly | 1 | 1 |
| Kevin Weisman | Craig Higgins | Anson Stokes | 1 | 1 |
| Krista Allen | Kristy Hopkins | Jade Blue Afterglow / Maitreya | 3 | 1 |
| Matthew Glave | Ken Bixler | FBI Prosecutor Kalembrenner | 1 | 2 |
| Michael Ensign | Judge Brenner | Dr. Barnes | 2 | 2 |
| Neal McDonough | Tommy Barnes | Agent Robert Comer | 1 | 2 |
| Nicki Aycox | Ellie Rebecca Brass | Chastity Raines | 1 | 1 |
| Robert Curtis Brown | Dan Keaton | Assistant DA Damon Kaylor | 1 | 1 |
| Rusty Schwimmer | Lorna Tenney | Bus Driver | 1 | 1 |
| Sal Landi | Carl Jansen | Agent Landau, Nicholas Regali | 1 | 2 |
| Sam Anderson | Dr. Mercer | U.S. Attorney Leamus | 1 | 1 |
| Silas Weir Mitchell | Willie Angel | Dougie | 1 | 1 |
| Stan Shaw | Geoff Johnson | Stephen Murdoch | 1 | 1 |
| Steve Hytner | John Claddon | Dr. Murphy | 1 | 1 |
| Tom Noonan | The Amazing Zephyr | John Lee Roche | 1 | 1 |
| Veronica Cartwright | Diane Ray | Cassandra Spender | 1 | 4 |
| Tony Amendola | Professor Rambar, The Super | Cigarette Smoking Pontiff | 3 | 1 |
| Colleen Flynn | Sister Alice | Colleen Azar, Michele Fazekas | 1 | 2 |
| Colton James | Chalie Easton, Zack Fenish | Josh Underwood | 2 | 1 |
| Cory Blevins | Surgeon | Missionary #1 | 2 | 1 |
| Jim Beaver | Stanley Tanner | Coroner | 2 | 1 |
| Lisa Darr | Gwen Anderson, Nicole Jones | Jana Fain | 2 | 1 |
| Michael B. Silver | Prosecutor | Howard Grodin | 1 | 2 |
| Dennis Boutsikaris | Dr. Sidney Buckman | Dr. Peter Voss | 1 | 1 |
| Diana-Maria Riva | Juanita | Angela Villareal | 1 | 1 |
| Jack Blessing | Officer Danny Finn | Dr. Jack Preijers | 1 | 1 |
| Jeff Bowser | Customer | Redhead Geek | 1 | 1 |
| John Aylward | Dr. Paul Anton | Dr. John Rietz | 1 | 1 |
| John Toles-Bey | Joe Boony | John Speranza | 1 | 1 |
| Kate McNeil | Sharon Woodbury | Nan Wieder | 1 | 1 |
| Kellie Waymire | Carla Dantini | Tammi Peyton | 1 | 1 |
| Leland Orser | Morris Pearson | Jason Ludwig | 1 | 1 |
| M.C. Gainey | Frank Maddox | Bo Taylor | 1 | 1 |
| Marshall Bell | Peter Hutchins Sr. | Commander Calvin Henderson | 1 | 1 |
| Michael Chieffo | Tom Roth | Carl Wade | 1 | 1 |
| Michael Massee | Stan Richardson | Vernon Ephesian | 1 | 1 |
| Micole Mercurio | Isabelle Millander | Miss Stodie | 1 | 1 |
| Patrick Renna | Security Guard | Ronnie Strickland | 1 | 1 |
| Paul Ben-Victor | Joey | Dr. Aaron Monte | 1 | 1 |
| Ramon Franco | Diego Barra | Nestor | 1 | 1 |
| Ron Canada | Jerry Barone | Franklin Potter | 1 | 1 |
| Scott Paulin | Dr. Parker | Jeffrey Conlon | 1 | 1 |
| Thomas Kopache | James Jasper | General Thomas Callahan | 1 | 1 |
| Wade Williams | Mr. Reston | Raymond Pearce | 1 | 1 |
| Will Sasso | Mason Lafoon | Lesley Stokes | 1 | 1 |
| Zach Grenier | Dr. Kachler | Herman Stites | 1 | 1 |
| George Murdock | Stuart Manslow | Elder #3 | 1 | 4 |
| Eddie Kaye Thomas | Seth Landers | Gary Cory | 1 | 2 |
| Michael Milhoan | Bartender | Dep. Arky Stevens | 2 | 1 |
| Tom O'Brien | Max Duncan | Corporal Frish | 1 | 2 |
| Bill Jacobson | Deputy Irons, Uniform | Gangbanger | 2 | 1 |
| Chad E. Donella | Vincent DeCarlo | Rob Roberts | 1 | 1 |
| Cheryl White | Mrs. Faith Mason | Nurse #3 | 2 | 1 |
| Cliff DeYoung | Mr. Del Negro | Mr. Jay Nemman | 1 | 1 |
| Coby Ryan McLaughlin | Derk Barlow | Young Agent #1 | 1 | 1 |
| Cyd Strittmatter | Dr. Wilson | Dr. Whitney Edwards | 1 | 1 |
| Cynthia Preston | Waitress | Nancy Aaronson | 1 | 1 |
| Erin Chambers | Molly Zimmerman | Anna Strong | 1 | 1 |
| Frank Military | Tyler Elliot | The Son / John | 1 | 1 |
| Greg Ellis | Fox Harris, Special Agent Sturgis | British Crewman #3 | 2 | 1 |
| Henri Lubatti | Charles Pinscher | Dr. Wilkenson | 1 | 1 |
| Jamie McShane | Eddie Vonner, Jeff Berlin | Injured Soldier | 2 | 1 |
| John Kapelos | Duke Rittle | Agent Fordyce | 1 | 1 |
| Laura Harris | Diane Kentner | Andrea | 1 | 1 |
| Laura Leigh Hughes | Mrs. Sorensen | Kersh's Assistant | 1 | 3 |
| Nancy Fish | Store Owner | Nurse Innes | 1 | 1 |
| Rebecca Wisocky | Shirley | Jackie Goldman | 1 | 1 |
| Rodney Eastman | Jacob Warren, Keith Driscoll | Ronald Purnell | 2 | 1 |
| Wayne Duvall | Walter Beerly | Agent Jerry Lamana | 1 | 1 |
| Zitto Kazann | Roman Wolenski | Caballero | 1 | 1 |
| Brian D. Johnson | Brad Malone, Manny Senteno | Man | 2 | 1 |
| Douglas Smith | Marlon West | Pitcher | 2 | 1 |
| Tom Virtue | Doctor, George | Dave Kline | 2 | 1 |
| A.J. Buckley | Ted Martin | Dude | 1 | 1 |
| Adam Nelson | Reed Collins | Mr. Van De Kamp | 1 | 1 |
| Alan Davidson | Nicco | Bearded Man | 1 | 1 |
| Caroline Lagerfelt | Marjorie Randell | Rustic Woman | 1 | 1 |
| Casey Biggs | Mr. Wilmot | Saksa | 1 | 1 |
| Dey Young | Agnes Goodwin | Judy Bishop | 1 | 1 |
| Frances Fisher | Joanna Sapphire | Lizzie Gill | 1 | 1 |
| Gregory Cruz | Gary Decker | Diego Garza | 1 | 1 |
| Jed Rees | Jay Finch | Lucas Menand | 1 | 1 |
| Jim Cody Williams | Happy Jack | Cal Jeppy | 1 | 1 |
| John Prosky | ADA Vanderpool | Medical Examiner | 1 | 1 |
| Katy Boyer | Laurianne Hastings | Dr. Lisa Holland | 1 | 1 |
| Michael Mantell | Dr. Stevens | Dr. James Riley | 1 | 1 |
| Michael McGrady | Sheriff Brackett | Sheriff Kurt Frey | 1 | 1 |
| Ming Lo | Anthony Pak | Dr. Kim | 1 | 1 |
| Spencer Garrett | Bob Fairmont | Harry Bring | 1 | 1 |
| Steve Rankin | Troy Thompson | U.S. Marshal Daddo | 1 | 1 |
| Steven Barr | Ranger | Courier Guard | 1 | 1 |
| Vic Polizos | Gus DiFusco | Agent Frank Burst | 1 | 1 |
| Vyto Ruginis | Phil Swelco | Lieutenant Bianco | 1 | 1 |
| Monnae Michaell | Deputy Marshal Karen Taylor, Doctor Orlander | Female Coroner | 2 | 1 |
| Nelson Mashita | E.R. Doctor | Dr. Lim | 1 | 2 |
| Wiley Pickett | Christian, Training Officer | Trooper #2 | 2 | 1 |
| Conrad Roberts | Palo Priest | Primitive African Man | 1 | 1 |
| Danielle Savre | Amy Keaton | Marcia Brady | 1 | 1 |
| David Wells | Elliot Beckman | Mr. Babbitt | 1 | 1 |
| Erich Anderson | Jack Garris | Doug Underwood | 1 | 1 |
| Joe Nieves | Javier Lileez | Barreiro's Son | 1 | 1 |
| Marcus Giamatti | Chevy Cigs | John Gillnitz | 1 | 1 |
| Megan Follows | Beth Darien | Kath McCready | 1 | 1 |
| Michael Wiseman | Director of Surveillance | Dr. Rocky Bronzino | 1 | 1 |
| Octavia Spencer | Sherry | Nurse | 1 | 1 |
| Robyn Lively | Joyce Dempsey | Angela Schiff | 1 | 1 |
| Roger Morrissey | Roger | Ubermenscher | 1 | 1 |
| Tara Karsian | Jill Paisley | Coroner's Assistant | 1 | 1 |
| Timothy Landfield | Alexander Woods | Professor Douglas Houghton, Scientist / Cobra | 1 | 2 |
| Todd Jeffries | Foreman | Lead Agent Mayfield | 1 | 1 |
| Valarie Pettiford | Susan Sue Latham | FBI Agent | 1 | 1 |
| Adam Lieberman | Dwight Connor | Transit Officer Philbrick | 1 | 1 |
| Brian George | Dr. Parayan | Project Doctor | 1 | 1 |
| Greg Anderson | Brian Clemonds | Photographer | 1 | 1 |
| Jeremy Roberts | Mr. Arnz | George Vincent | 1 | 1 |
| Jonathan Fraser | Kevin Shepherd | Uniformed Cop | 1 | 1 |
| Keith Szarabajka | Randy | Anthony Tipet | 1 | 1 |
| Louis Ferreira | Ken Wellstone | Detective Costa | 1 | 1 |
| Mari Weiss | Foreman | I.C.U. Nurse | 1 | 1 |
| Noel Gugliemi | David Ramirez | Gangbanger #1 | 1 | 1 |
| Pat Destro | Mary Acheson | Joan Scobie | 1 | 1 |
| Rick Cramer | Captain Mike Wilson | Guard | 1 | 1 |
| Susan Slome | Female Passenger | Woman at O.A. | 1 | 1 |
| Wendie Malick | Donna Eiger | Assistant Director Maslin | 1 | 1 |
| Ben Reed | Willis | Officer | 1 | 1 |
| David Fabrizio | Thomas Simon | E.R. Physician | 1 | 1 |
| David Figlioli | Green Poncho | Victor Dale Potts | 1 | 1 |
| Grant Heslov | Coroner Corbett | Dr. Andre Bormanis | 1 | 1 |
| John Billingsley | Paul Cyden | Timothy "Timmy the Geek" Landau | 1 | 1 |
| Monique Edwards | Nurse Nanette Faber | Head Teller | 1 | 1 |
| Rachel Winfree | Janet | Nurse | 1 | 1 |
| Stephen Snedden | Steven Dougherty | James "Jimmy" Bond | 1 | 1 |
| Christopher Jacobs | Luke | E.R. Doctor | 1 | 1 |
| Kim Robillard | Trucker | Homer | 1 | 1 |
| Lombardo Boyar | Jesse Commons | Deputy Juan Molina | 1 | 1 |
| Madison Mason | Vance Colton | Captain Yip Harburg | 1 | 1 |
| Maria Celedonio | Melanie | Chantara Gomez | 1 | 1 |
| Chet Grissom | Restaurant Manager | Detective | 1 | 1 |
| Dale Dickey | Waitress | Game Warden | 1 | 1 |
| James Parks | Jonathan Wax | Agent Terry Sullivan | 1 | 1 |
| Jim Hanna | Jack | Koko's Manager #2 | 1 | 1 |
| Larry Udy | Patron #1 | Middle-Aged Man | 1 | 1 |
| Ric Sarabia | Fight Doctor | Prison Trustee | 1 | 1 |
| Roz Witt | Blue Hair | Night Nurse | 1 | 1 |
| Gary Bristow | Chuck Hastings | Howard Salt | 1 | 1 |
| Andy Umberger | Rob Rhoda | Agent Chesty Short | 1 | 1 |
| Kevin E. West | Ray Gaynor | Navy Seal | 1 | 1 |
| Scott Alan Smith | Stuart Gardner | Prison Doctor | 1 | 1 |
| Wayne Thomas Yorke | CSI Tech | Workman #1 | 1 | 1 |
| Brian Catalano | Campus Security Officer #1 | Passenger Agent | 1 | 1 |
← CSI: Crime Scene Investigation × The X-Files
Cast data from TVmaze, licensed CC BY-SA 4.0.