All 94 actors in both ER and Two and a Half Men
94 actors have appeared in both ER and Two and a Half Men, across 593 episodes. The most-credited is Lyn Alicia Henderson, Paramedic Pamela Olbes in ER and Patricia in Two and a Half Men.
| Actor | In ER | In Two and a Half Men | Eps | Eps |
|---|---|---|---|---|
| Lyn Alicia Henderson | Paramedic Pamela Olbes | Patricia | 149 | 1 |
| Judy Greer | Tildie Mulligan | Bridget, Myra, Danny | 1 | 13 |
| Ming-Na Wen | Dr. Jing-Mei "Deb" Chen | Linda Harris | 8 | 5 |
| Maggie Lawson | Shannon Mitchell | Ms. McMartin | 1 | 10 |
| Conchata Ferrell | Mrs. Jenkins | Berta | 1 | 8 |
| Liz Vassey | Liz | Michelle, Kate | 4 | 4 |
| Stacy Keach | Mike Gates | Tom | 3 | 4 |
| Brendan Patrick Connor | Paramedic Reidy | Clive, Middle-Aged Guy | 13 | 2 |
| Katherine LaNasa | Janet Wilco | Lydia | 1 | 4 |
| Emily Rose | Dr. Tracy Martin | Janine | 11 | 1 |
| John Stamos | Dr. Tony Gates | John Stamos, prospective home buyer | 2 | 2 |
| Michael Patrick McGill | Detective Ed Bernstein, Security #1, Officer Jeffries | Joseph, Officer Smith | 6 | 2 |
| Myndy Crist | Valerie Page | Wendy | 2 | 1 |
| Rhyon Nicole Brown | Erika Crawford, Wendy | Ashley | 2 | 1 |
| Sara Rue | Jane | Naomi | 1 | 2 |
| Vernée Watson | April Wilson | Nurse, Karen | 2 | 4 |
| Iqbal Theba | Dr. Zogoiby | Don | 4 | 1 |
| Angus T. Jones | Sean Gattney | Jake Harper | 1 | 1 |
| Darryl Sivad | Colin | Cab Driver | 1 | 1 |
| Diane Delano | Stella Willis, Delores | Prison Matron | 5 | 1 |
| Julie Berman | Jessamyn Chadsey | Sarah | 1 | 1 |
| Stephanie Erb | Mrs. Kinney | Mrs. Schmidt | 1 | 1 |
| Erin O'Shaughnessy | Christine | Mother | 2 | 1 |
| Juliette Goglia | Sydney Carlyle | Joanie | 1 | 2 |
| Sandra Purpuro | Mrs. Perrault | Cynthia, Mona | 1 | 2 |
| Wayne Wilderson | Dr. Claypool | Dad, Roger | 1 | 2 |
| Joe Manganiello | Officer Litchman | Alex | 4 | 1 |
| Arthur Darbinyan | Mr. Papazian | Joe | 1 | 1 |
| Brian Turk | Michaels | Mike | 1 | 1 |
| Christopher T. Wood | Dr. Higgins | Arnold | 1 | 1 |
| Deena Dill | Kristy | Miss Tuttle | 1 | 1 |
| Eugene Byrd | James Connor | Lenny | 1 | 1 |
| Eve Gordon | Mrs. Nugent | Brenda | 1 | 1 |
| Frances Fisher | Helen Kingsley | Priscilla Honeycutt | 1 | 1 |
| Garry Marshall | Harry Feingold | Garry | 1 | 1 |
| Jonathan Banks | Robert Truman | Sid | 1 | 1 |
| Kate Miner | Marcia | Nadine | 1 | 1 |
| Kay Panabaker | Melissa Rue | Sophie | 1 | 1 |
| Lori Lively | Helen | Kathy | 1 | 1 |
| Madison Mason | Clive King | Tommy Pearson | 1 | 1 |
| Marco Sanchez | O'Connor | Hector | 1 | 1 |
| Marilu Henner | Linda | Linda | 1 | 1 |
| Mark Chaet | Tim | Doctor | 1 | 1 |
| Richard Riehle | Mandrake Patient | Santa | 1 | 1 |
| Richard Whiten | Lawyer | Officer Bryant, Sergeant Preston | 1 | 2 |
| Steffani Brass | Shelly Burke | Amy, Debbie | 1 | 2 |
| Steve Tom | MacPherson | Minister | 1 | 2 |
| Tom Virtue | Pares | Freddy The Minister, Stan | 1 | 2 |
| George Wyner | Rabbi | Sheldon | 2 | 1 |
| Stacey Travis | Detective Weller | Linda | 2 | 1 |
| Alex Kapp | Brenda | Donna | 1 | 1 |
| Amy Farrington | Sandy Mader | Kathleen | 1 | 1 |
| Audrey Wasilewski | Officer Wetterling | Megan | 1 | 1 |
| Bellamy Young | Grace | Diane | 1 | 1 |
| Bradley Snedeker | Officer Jimmy Howe | M.P. Ross | 1 | 1 |
| Cristine Rose | Mrs. Martinez | Lenore | 1 | 1 |
| David Denman | Jeremy Willis / "Angel" | Jack | 1 | 1 |
| Diane Sellers | Mrs. Garrison | Ms. Gallagher | 1 | 1 |
| Ewan Chung | Chiu | Attendant | 1 | 1 |
| Jenn Liu | Rocker Girl | Gwyneth | 1 | 1 |
| Jennifer Hale | Gloria | TV Announcer | 1 | 1 |
| Judith Drake | Greta | Cynthia | 1 | 1 |
| June Squibb | Social Security Daughter | Margaret | 1 | 1 |
| Nadine Ellis | Mason's Wife | Jeanie | 1 | 1 |
| Nicole J. Butler | Anesthesiologist | Mother | 1 | 1 |
| Sab Shimono | Dr. Okida | Hiroshi | 1 | 1 |
| Ken Davitian | Zakar Papazian | Mr. Mardirosian | 2 | 1 |
| Amy Pietz | Loren | Angie | 1 | 1 |
| Bob Rusch | Lillion | Referee | 1 | 1 |
| Bruno Amato | Sheriff | Officer Roberts | 1 | 1 |
| Charlie Dell | Circumcision Patient | Minister | 1 | 1 |
| Eddie Shin | Med Student Stanley Mao | Dr. Kim | 2 | 1 |
| Elaine Hendrix | Brinn | Sylvia | 1 | 1 |
| Jackie Debatin | Judy | Ginger | 1 | 1 |
| Jacob Urrutia | Jose Rodriguez | Luis | 2 | 1 |
| Jamie Rose | Marilyn Bracken | Sloane Jagov | 1 | 1 |
| Ken Lerner | Harry Stopak, Stan Seidel | Dr. Levine | 2 | 1 |
| Lamont Thompson | Paul GIlliam | Bruno | 1 | 1 |
| Lisa Arning | Nikki | Cheryl Ann | 1 | 1 |
| Nancy Linari | Elizabeth Puro | Woman's Voice | 1 | 1 |
| Alessandra Torresani | Kate Preston | Kathy | 1 | 1 |
| Bob Rumnock | Phillip Berk | Minister | 1 | 1 |
| Cheryl White | Meryl Sites | Ruth | 1 | 1 |
| Elizabeth Bogush | Debra Strickland | Emily | 1 | 1 |
| Frankie Jay Allison | Frankie | Rodney | 1 | 1 |
| Jay Harik | Seiger | Cab Driver | 1 | 1 |
| Jim Piddock | Dr. Earl Whitehead | Edward | 1 | 1 |
| Jonathan Palmer | Dr. Blevins | James | 1 | 1 |
| Chris Coppola | Cop | Douglas | 1 | 1 |
| Rod Britt | Mr. Helpful | Man | 1 | 1 |
| Sonia Jackson | Ruthie Newton | Andrea | 1 | 1 |
| Ping Wu | Mr. Cheung | Coroner | 1 | 1 |
| Michael Edwin | Drunk Man | Proprietor | 1 | 1 |
| Alexis Krause | Mallory | Kelly | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.