All 144 actors in both Grey's Anatomy and Lie to Me*
144 actors have appeared in both Grey's Anatomy and Lie to Me*, across 515 episodes. The most-credited is Jerrika Hinton, Dr. Stephanie Edwards in Grey's Anatomy and Robin in Lie to Me*.
| Actor | In Grey's Anatomy | In Lie to Me* | Eps | Eps |
|---|---|---|---|---|
| Jerrika Hinton | Dr. Stephanie Edwards | Robin | 21 | 1 |
| Teresa Huang | Nurse Ruth | Nurse | 19 | 1 |
| Melissa George | Sadie Harris | Clara Musso | 8 | 3 |
| Rebecca Field | Sabine McNeil | Jenna Bynes | 7 | 1 |
| Hayley McFarland | Rory Williams | Emily Lightman | 1 | 5 |
| Daniel Sunjata | Nurse Eli | Andrew Jenkins | 8 | 1 |
| J.D. Cullum | Lloyd, Representative | Dr. Dembeck | 3 | 1 |
| David Anders | Jim | Staff Sgt. Russell Scott | 2 | 1 |
| Dean Norris | Vince | Dawkins | 2 | 1 |
| Raphael Sbarge | Paul | Prosser | 2 | 1 |
| Sherri Saum | Allison Robin Brown | Candice McCallister | 2 | 1 |
| Frankie Faison | William Bailey | Teddy | 4 | 1 |
| Shoshannah Stern | Dr. Lauren Riley | Sarah | 2 | 3 |
| Janora McDuffie | Janet Anderson | McKenzie Dodd | 6 | 1 |
| Kristen Ariza | Angela | Heidi | 1 | 10 |
| Bruce Weitz | Mr. Edward Levangie | Leo O'Sullivan | 1 | 1 |
| James Frain | Tom Crawley | McClellan | 1 | 1 |
| Todd Stashwick | Mr. Kramer | Hugh Ellis | 1 | 1 |
| Anjul Nigam | Dr. Raj Sen | Shreyas Patel | 4 | 1 |
| Sam Page | Sam Sutton | George Parker | 4 | 1 |
| Tim Griffin | Ronny O'Malley | Principal Castle | 5 | 1 |
| Troy Winbush | Darren Riley | Wallace | 3 | 1 |
| Annette O'Toole | Madeleine Skurski | Veronica | 1 | 1 |
| Brent Sexton | Jerry Frost | Thomas Fletcher | 1 | 1 |
| Brian Howe | Robert Fischer | Garrett Denning | 1 | 1 |
| Clea DuVall | Jennifer Robinson | Michelle Russell | 2 | 1 |
| D.W. Moffett | Allan | Dr. Jeffrey Buchanan | 1 | 1 |
| Dave Shalansky | Jeremy | Harvey | 2 | 1 |
| Grace Bannon | Alice Kepner | Danielle Stark | 2 | 1 |
| Joseph Lyle Taylor | Weiss | Cab Driver | 1 | 1 |
| Josh Stamberg | Tommy Walker | AUSA Hutchinson | 1 | 1 |
| Katherine LaNasa | Kalpana Vera | Laura Cross | 1 | 1 |
| Kathleen Rose Perkins | Sarah | Colette Bradley | 1 | 1 |
| Kevin Rankin | Jack Vaughan | Kent Clark | 2 | 1 |
| Michael Beach | Mr. Baker | James | 1 | 1 |
| Patrick Fischler | Jake Steiner | Olson | 1 | 1 |
| Rance Howard | Martin Carroll | Joe Metz | 1 | 1 |
| Robert Wisdom | Mr. Hamilton | Bonds | 1 | 1 |
| Tiffany Hines | Natalie | Lacey | 2 | 1 |
| Dominic Hoffman | Dr. Jeff Russell | Sec. Deputy Dawkins | 4 | 1 |
| Brian Tee | Andrew 'Andy' Billings | Han Yong-Dae | 2 | 1 |
| Dan Martin | Scott Hill | Conrad Ricks | 2 | 1 |
| John Bishop | James Carlson | Ray "Romeo" Blake | 2 | 1 |
| Theo Rossi | Stan Giamatti | Tressler | 2 | 1 |
| Arye Gross | Adam Morris | Dr. Hamill | 1 | 1 |
| Currie Graham | Greg | Eric Kuransky | 1 | 1 |
| Dylan Minnette | Ryan | Noah Marber | 1 | 1 |
| Glenn Morshower | Walter | Col. Gorman | 1 | 1 |
| Hayley Chase | Cassidy Gardner | Liz | 1 | 1 |
| Kari Coleman | Mother | Mary | 1 | 1 |
| Lauren Bowles | Alice Franklin | Valerie Blunt | 1 | 1 |
| Lisa Waltz | Margot Billings | Mrs. Roland | 1 | 1 |
| Madeline Carroll | Ivy Soltanoff | Samantha Burch | 1 | 1 |
| Mark Harelik | Keith Polus | DNI Mercier | 1 | 1 |
| Spencer Garrett | Jim Walker | Mr. Anders | 1 | 1 |
| Tzi Ma | Mr. Patterson | Mr. Chen | 1 | 1 |
| Amy Rosoff | Kira Donnelly | Private Rebecca Metz | 1 | 1 |
| Barry Shabaka Henley | Mr. Patterson | Dr. Olson | 1 | 1 |
| Catherine Dent | Cathy Rogerson | Faye Sheridan | 1 | 1 |
| Christopher Thornton | Daniel Campbell | Johnny Wheels | 1 | 1 |
| D.B. Woodside | Marcus King | Henry Strong | 1 | 1 |
| David Rees Snell | Richy Rich | Kevin Wilkie | 1 | 1 |
| Haley Ramm | Shannon | Amy | 1 | 1 |
| James Immekus | Andrew Langston | Jake Hartman | 2 | 1 |
| Jessica Tuck | Shannon's Mom | Deputy Warden Lamb | 1 | 1 |
| Joy DeMichelle | Gladys | Kay Norton | 2 | 1 |
| Kenneth Mitchell | Wade Solomon | Duane Corey | 1 | 1 |
| Lindsey Kraft | Lisa Campbell | Connie | 1 | 1 |
| Mandy June Turpin | Karla | Carolyn Hollin | 1 | 1 |
| Mekenna Melvin | Katie | Stefanie | 1 | 1 |
| Michole White | Hillary | Merrick | 1 | 1 |
| Pej Vahdat | Tarik Amin | Jason Kashani | 1 | 1 |
| Regi Davis | Dr. Kevin Fisher | Marshal Keller | 2 | 1 |
| Rowena King | Celeste Newman | Helen Dezekis | 1 | 1 |
| Alison La Placa | Mrs. Nolston | Diane Ktretschmer | 2 | 1 |
| Jos Viramontes | David Martinez | Dr. Blake | 2 | 1 |
| Kathryn Meisle | Liz Monroe | Mary Cole | 2 | 1 |
| April Grace | Greta's Sister | Mrs. Lennox | 1 | 1 |
| Arlene Tur | Pamela Calva | Kimi | 1 | 1 |
| Erica Piccininni | Barbara Collins | Joanna | 1 | 1 |
| José Zúñiga | Anthony Meloy | Detective Molina | 1 | 1 |
| Lee Garlington | Farah Linden | Mrs. Walker | 1 | 1 |
| Michael McGrady | Stanley Singer | Gil Wallace | 1 | 1 |
| Paul James | Eric | Kyle | 1 | 1 |
| Ramón de Ocampo | James Benton | Michael | 1 | 1 |
| Rob Brownstein | Larry | Secretary Adam Miller | 1 | 1 |
| Stacy Edwards | Kathleen Wheeler | Dr. Christina Knowlton | 1 | 1 |
| Sunkrish Bala | Steve Murphy | Arun Ashraf | 1 | 1 |
| Cheryl White | Lynn Connors | Mayor Meredith Fallon | 1 | 1 |
| Dana Sorman | Sharon | Lawyer | 1 | 1 |
| David Grant Wright | Mr. Burton | Dean Warren | 1 | 1 |
| Isabella Hofmann | Irene Waller | Judge Kathleen Stark | 1 | 1 |
| Jeffrey Addiss | Greg | Porsche Driver | 1 | 1 |
| Michael Patrick McGill | Bob Corson | Officer Barnes | 1 | 1 |
| Patrick Cavanaugh | Vince Cruse | Garret Craywood | 1 | 1 |
| Sage Ryan | Kyle Baker | Jake Turley | 1 | 1 |
| Steven Flynn | Scott Robinson | Keith Berenson | 1 | 1 |
| Tom Verica | Michael Norris | Paul Aronson | 1 | 1 |
| Bernard White | Dr. Darwich | Imam Amir Hadad | 1 | 1 |
| Kelvin Han Yee | Dr. James Lew | Ambassador Park Jung-Soo | 1 | 1 |
| Rubén Garfias | Bob | Colombian Mayor | 1 | 1 |
| Tyrees Allen | Dr. Saltzman | DNC Chairman Baldridge | 1 | 1 |
| Alina Phelan | Karen Marks | Joan | 1 | 1 |
| Anthony Azizi | Syrian Doctor | Omar Kahn | 1 | 1 |
| B.K. Cannon | Girl Band Geek | Stacey | 1 | 1 |
| Hayley Holmes | Kimmy | Carley | 1 | 1 |
| Kelvin Brown | Frankie | Henrik | 1 | 1 |
| Laura Kenley | Janie | Michelle Daly | 1 | 1 |
| Marc Vann | Hematologist | Jim Gunderson | 1 | 1 |
| Mark Berry | AA Member | Mr. McNeil | 1 | 1 |
| Scott Klace | Dr. Jordan Wagner | Martin Wexler | 1 | 1 |
| Barry Livingston | Wayne Sheehan | Attorney | 1 | 1 |
| Bob Gebert | Mario | Moss | 1 | 1 |
| Brian Oblak | Daniel Rudin | FBI Agent #1 | 1 | 1 |
| Chris McGarry | Danny Wayne | FEMA Commander Stevens | 1 | 1 |
| Nadine Ellis | Melissa Walker | Female Secret Service Agent | 1 | 1 |
| Nicole DuPort | Theresa | Marla Seeger | 1 | 1 |
| Gary Kraus | Louis Cardon | Bus Driver | 1 | 1 |
| Harrison Knight | Andrew Willis | Andre Ricks | 1 | 1 |
| Kosha Patel | Tia | Kiran Purohit | 1 | 1 |
| Michael Esparza | Marcus | Eric / Charlie Three | 1 | 1 |
| Steve Mize | Scott Burke | Nick | 1 | 1 |
| Zachary Knower | Nick Kelsey | Videographer 1 | 1 | 1 |
| Alex Stamm | Josh Shelton | Jared | 1 | 1 |
| Chase Kim | Lawyer | Korean American Secret Service Agent | 1 | 1 |
| Craig Tsuyumine | TV Reporter | Player #5 | 1 | 1 |
| David J. Lee | Man In Clinic | Groomsman 1 | 1 | 1 |
| Fred Ochs | Mr. Kaplan | Craig Snell | 1 | 1 |
| Grinnell Morris | Intern #4 | Paul Russell | 1 | 1 |
| Lou Richards | Steven Basche | Robert Bradin | 1 | 1 |
| Lydia Castro | Marilyn Rocher | Platoon Mate #3 | 1 | 1 |
| Marcuis Harris | Rob Mays | Male Protester #2 | 1 | 1 |
| Tom Choi | Flouroscope Tech | Groom | 1 | 1 |
| Gary Carlos Cervantes | Mr. Calva | ATF Asst. Dir. | 1 | 1 |
| Jason Kelley | Chuck | Uniform Cop #1 | 1 | 1 |
| Robert Alan Beuth | Mr. Gordor | Angry Guest | 1 | 1 |
| Vincent Duvall | Rick Henry | Handsome Guy | 1 | 1 |
| Amy Cale Peterson | Nurse Home Staffer | Mortage Manager | 1 | 1 |
| Shelley Robertson | Arlene Travis | Female Protester | 1 | 1 |
| Liza de Weerd | Woman | Anne-Marie McDermott | 1 | 1 |
| Ross Mackenzie | Dr. Mitchell | FEMA Tech | 1 | 1 |
| Stacey Moseley | Donna | ICU Nurse | 1 | 1 |
| Michelle Noh | Sharon Peterson | Corporate Woman | 1 | 1 |
| Bob Bledsoe | Man | Hot Truck Guy | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.