All 66 actors in both Grey's Anatomy and The Big Bang Theory
66 actors have appeared in both Grey's Anatomy and The Big Bang Theory, across 746 episodes. The most-credited is Carol Ann Susi, Mrs. Dorsokowski in Grey's Anatomy and Mrs. Wolowitz in The Big Bang Theory.
| Actor | In Grey's Anatomy | In The Big Bang Theory | Eps | Eps |
|---|---|---|---|---|
| Carol Ann Susi | Mrs. Dorsokowski | Mrs. Wolowitz | 1 | 39 |
| Brian George | Emile Flores | Dr. V.M. Koothrappali | 1 | 16 |
| Laurie Metcalf | Beatrice Carver | Mary Cooper | 1 | 14 |
| Joshua Malina | Seth Hammer | President Siebert | 1 | 13 |
| Aarti Mann | Holly Harner | Priya | 1 | 12 |
| Laura Spencer | Lacey | Emily Sweeney | 1 | 12 |
| Dean Norris | Vince | Colonel Williams | 2 | 6 |
| Peter MacNicol | Dr. Robert Stark | Dr. Wolcott | 7 | 1 |
| Casey Sander | Casey | Mike Rostenkowski | 1 | 6 |
| Mark Harelik | Keith Polus | Dr. Eric Gablehauser | 1 | 5 |
| Sara Gilbert | Kim Allen | Leslie Winkle | 1 | 5 |
| Margo Harshman | Jennifer Morris | Alex Jensen | 1 | 4 |
| Lance Barber | Phil | George Cooper Sr., Jimmy Speckerman | 1 | 2 |
| Michelle Arthur | Brooke | Mrs. Petrescu | 1 | 2 |
| Summer Glau | Nurse Emily Kovach | Summer Glau | 2 | 1 |
| Elizabeth Bogush | Gia | Dr. Catherine Millstone | 1 | 1 |
| Frank Maharajh | Paramedic | Venkatesh | 1 | 1 |
| Jim Turner | Dr. Schacter | Reverend White | 1 | 1 |
| Joel Murray | ICE Agent Martin Fields | Doug | 1 | 1 |
| Julio Oscar Mechoso | Chucky Eaton | Officer Hackett | 1 | 1 |
| Kelli Goss | Laura | Chelsea | 1 | 1 |
| Troy Winbush | Darren Riley | Paramedic | 3 | 1 |
| Annie O'Donnell | Older Woman | Mrs. Fowler, Mrs. Lorvis | 1 | 2 |
| Caleb Pierce | Charlie Patterson | Jess | 1 | 2 |
| Emily Happe | Libby Kepner | Kathy O'Brien | 2 | 1 |
| Erin Allin O'Reilly | Jodi | Cheryl | 1 | 2 |
| Phil Abrams | Dr. Jim Nelson | Dr. Bernstein | 3 | 1 |
| Artie O'Daly | Intern #3 | Young Man | 1 | 1 |
| Becky O'Donohue | Jenna | Siri | 1 | 1 |
| Brooke Baumer | Obstetrician | Denise | 1 | 1 |
| D'Kia Anderson | Day Care Worker | Hostess | 1 | 1 |
| Jane Galloway Heitz | Annie's Mother | Mildred | 1 | 1 |
| Judith Moreland | Mrs. Baer | Jan | 1 | 1 |
| June Squibb | Dr. Elsie Clatch | Meemaw | 1 | 1 |
| Kevin Brief | Barry Taylor | Glen, Security Guard | 1 | 2 |
| Meagen Fay | Paula | Mrs. Rostenkowski | 1 | 1 |
| Michael Hyatt | Mariann Davidson | Charlotte | 1 | 1 |
| Michael Patrick McGill | Bob Corson | Police Officer | 1 | 1 |
| Tiffany Dupont | Zoe | Angela | 1 | 1 |
| Treisa Gary | Beth | Waitress | 1 | 1 |
| Wayne Wilderson | Bill Adams | Travis | 1 | 1 |
| Hilda Boulware | Ante Ndugu | Woman | 3 | 1 |
| Lindsey Kraft | Lisa Campbell | Marissa | 1 | 2 |
| Amanda Payton | Dr. Daphne Lopez | Ainsley | 1 | 1 |
| Chriselle Almeida | Jaclyn Werlein | Lakshmi | 1 | 1 |
| Courtney Ford | Jill Meyer | Alice | 1 | 1 |
| Edward James Gage | Adam Keller | Mailman | 1 | 1 |
| Jason Kravits | Chuck Rubin | Danny | 1 | 1 |
| Karl T. Wright | Divorce Mediator | Jimmy | 1 | 1 |
| Kimberly Hébert Gregory | Deborah Curzon | Ms. Davora | 1 | 1 |
| Matt Bennett | Steve | Josh | 1 | 1 |
| Sarayu Blue | Pam | Lalita Gupta | 1 | 1 |
| Angela Lin | Barbara Yu | Maritza | 1 | 1 |
| Anil Margsahayam | Dr. Barrett | Man | 1 | 1 |
| Lauri Johnson | Grandma Ruth | Mrs. Gunderson | 1 | 1 |
| Mark Berry | AA Member | Pit Boss | 1 | 1 |
| Monica Garcia | Peds Nurse | Maria | 1 | 1 |
| Nicole J. Butler | Jess | Clerk | 1 | 1 |
| Rick Gifford | Davis Calder | Guy | 1 | 1 |
| Sharon Omi | Worried Tenant | Nurse in Biohazard Suit | 1 | 1 |
| Amy Tolsky | Tonya Orvis | Joan | 1 | 1 |
| Jack McBrayer | Tom Costello | Randall | 1 | 1 |
| Jan Hoag | Wheezing Patient | Lilian | 1 | 1 |
| Susan Chuang | Naomi Evans | Dr. Harris | 1 | 1 |
| Tonja Kahlens | Courtney Swanson | Woman | 1 | 1 |
| Andy Kim | Father | Tour Guide | 1 | 1 |
← Grey's Anatomy × The Big Bang Theory
Cast data from TVmaze, licensed CC BY-SA 4.0.