All 128 actors in both Grey's Anatomy and The Middle
128 actors have appeared in both Grey's Anatomy and The Middle, across 682 episodes. The most-credited is Brandon Scott, Intern Ryan in Grey's Anatomy and Cory in The Middle.
| Actor | In Grey's Anatomy | In The Middle | Eps | Eps |
|---|---|---|---|---|
| Brandon Scott | Intern Ryan | Cory | 13 | 1 |
| Grace Bannon | Alice Kepner | Ruth | 2 | 12 |
| Natalie Lander | Judith Dunn | Debbie | 1 | 13 |
| Jack McBrayer | Tom Costello | Dr. Ted Goodwin | 1 | 10 |
| Winston Story | Dr. Leo Byrider | OWP GUy | 20 | 1 |
| Peter Breitmayer | Carson Methodist Doctor | Pete Miller | 1 | 12 |
| Doris Roberts | Gladys Poulter | Mrs. Rinsky | 1 | 3 |
| Mitch Silpa | Tim Ruggles | Todd | 2 | 1 |
| Mason Cook | Casey | Corey | 1 | 4 |
| Greg Cromer | Dana | Coach Emerson | 1 | 3 |
| Marion Ross | Betty Donahue | Ms. Dunlap | 1 | 1 |
| Suzy Nakamura | Jenn Smith | Beth | 1 | 1 |
| Ginny McMath | Irene | Darrin's Mom, Peg | 1 | 4 |
| Andy Milder | Dr. Darryl Nessbaum | Principal Sholin | 1 | 2 |
| Celia Finkelstein | Nurse Bridget Irving | Colleen | 2 | 1 |
| Lauri Johnson | Grandma Ruth | Mrs. Hilsabeck | 1 | 2 |
| Casey Sander | Casey | Jack Tracy | 1 | 3 |
| Emily Rutherfurd | Nancy Karev | Dierdre Peterson, Deidre Peterson | 1 | 3 |
| Phil Abrams | Dr. Jim Nelson | Robert | 3 | 1 |
| Roger Rees | Dr. Colin Marlowe | Mr. Glover | 3 | 1 |
| Thomas F. Duffy | The Hammer | Jack Meenahan | 1 | 3 |
| Kayla Madison | Allegra | Shelly Donahue | 1 | 6 |
| Audrey Wasilewski | Nicole Waldman | Jody | 1 | 1 |
| Charles Emmett | Mr. Bosson | Security Guy | 1 | 1 |
| Dawn Joyal | Nurse Jane Rogers | Jill Hobert | 2 | 2 |
| Judith Hoag | Rhada Douglas | Mrs. Jennings | 2 | 1 |
| Karly Rothenberg | Ruth Bennet | Woman | 1 | 1 |
| Laura Heisler | Carla | Lisa the Librarian | 1 | 2 |
| Lisa Rothschiller | Supervisor Lisa | Scary Woman | 3 | 1 |
| Mackenzie Brooke Smith | Ella | Megan | 1 | 4 |
| Michael Patrick McGill | Bob Corson | Cop #1 | 1 | 1 |
| Rose Abdoo | Dr. Dawson | Mrs. Kozicki | 1 | 1 |
| Chase Kim | Lawyer | George Chung | 1 | 3 |
| Carlease Burke | Mrs. Gates | Ms. Teegarden, Professor Lynch | 1 | 2 |
| Gina Hecht | Mrs. Sutton | Ms. Schaefer | 1 | 2 |
| Liz Montgomery | Woman In ER | Lisa the Librarian | 1 | 2 |
| Terrell Ransom Jr. | Arthur Krug | Boy, Spencer | 1 | 2 |
| Alan Rachins | Louie | Mort | 1 | 1 |
| Dale Dickey | Emily "Gasoline" Bennett | Sandy | 1 | 1 |
| Gina Gallego | Lucia Torres | Senora Pitts | 1 | 1 |
| Rebecca Metz | Brenda Lawson | Saleslady | 1 | 1 |
| Robert Pine | Vincent | Mr. Travers | 1 | 1 |
| Ron Roggé | Fire Captain | Dad | 1 | 1 |
| Vicki Davis | Morgan Fisher | Debbie | 1 | 1 |
| Jon Curry | Fred Fisher | Corporate Guy #2, Jeffrey | 1 | 2 |
| Sonya Leslie | Rita | Saleswoman, Woman #2 | 1 | 2 |
| Timothy E. Goodwin | Len | Dalton, Man | 1 | 2 |
| Ty Chen | Frat Kid | Scott | 1 | 2 |
| Adam Kulbersh | Tommy | Mailman | 1 | 1 |
| Alex Alexander | Annie Connors | Woman | 1 | 1 |
| Amy Farrington | Mary May | Gail | 1 | 1 |
| Barry Livingston | Wayne Sheehan | Milt | 1 | 1 |
| Brian Howe | Robert Fischer | Tom Hanson | 1 | 1 |
| Casey Wilson | Courtney Hall | Reverend Tammy | 1 | 1 |
| Cooper Roth | Brendon Browning | Gibson | 1 | 1 |
| Dale Raoul | NICU Nurse | Guidance Counselor | 1 | 1 |
| Dale Waddington Horowitz | OB Resident | Room Mom | 2 | 1 |
| Danielle Kennedy | Angry Woman | Alice | 2 | 1 |
| Eve Brenner | Enid | Mrs. Perkins | 1 | 1 |
| Jan Hoag | Wheezing Patient | Nurse Fahler | 1 | 1 |
| Jeris Lee Poindexter | Mr. Strickland | Janitor, Old Man | 1 | 2 |
| Mark Daugherty | Evan | Matt | 1 | 2 |
| Mary Pat Gleason | Marge Walker | Mrs. Colavita | 1 | 1 |
| Paul McKinney | Julian Fisher | Tennis Ref | 1 | 1 |
| Scott Michael Morgan | Patient #2 | Chuck | 1 | 1 |
| Skyler James | Pete Hover | Bowling Son, Dante | 1 | 2 |
| Susan Berger | Lee | Bingo Lady | 1 | 1 |
| Vicki Lewis | Harriet | Carol Barry | 1 | 1 |
| Victoria Kelleher | James's Mother | Gifted Mom | 1 | 1 |
| Vito Viscuso | Pilot | Man #1 | 1 | 1 |
| Wayne Wilderson | Bill Adams | Principal Carson | 1 | 1 |
| Mackenzie Aladjem | Emma | Hayley | 1 | 2 |
| Ursula Burton | E.R. Nurse | Jill Hobert | 2 | 1 |
| Ben Stillwell | James Leggett | Bartender | 1 | 1 |
| Mark L. Taylor | Dave Buckley | Mr. Callen | 1 | 1 |
| Mary Passeri | Jeannie Reed | Mrs. Seabrook | 1 | 1 |
| Miriam Flynn | Ms. Bitzer | Female Clerk | 1 | 1 |
| Romel De Silva | Screaming Patient | London Calling Teammate | 1 | 1 |
| Stacy Barnhisel | Gretchen | Kristy | 1 | 1 |
| Treisa Gary | Beth | Customer | 1 | 1 |
| Wesley Thompson | Therapist | Cop | 1 | 1 |
| Brian Chenoweth | Scared Guy | BMV Examiner | 1 | 2 |
| Hayley Holmes | Kimmy | Girl, Nikki | 1 | 2 |
| Alex Stamm | Josh Shelton | Ticket Seller | 1 | 1 |
| Ashlee Füss | Lisa Wilcox | Maddie | 1 | 1 |
| Brian Scolaro | Mike | Mickey | 1 | 1 |
| Doug Sinclair | Brett Hayes | Coach | 1 | 1 |
| Gary Kraus | Louis Cardon | Coach | 1 | 1 |
| Jonathan Goldstein | Ken May | Professor Mark Beckett | 1 | 1 |
| Lise Simms | Karen | Woman | 1 | 1 |
| Rusty Burns | Reporter #2 | Sandy | 1 | 1 |
| Sally Ann Brooks | Marie Lamott | Jocelyn | 1 | 1 |
| Santiago Segura | Chad | Player #1 | 1 | 1 |
| Sara Van Horn | Nash's Grandma | Woman | 1 | 1 |
| Sydney Sweeney | Erin Weaver | Female Student 1 | 1 | 1 |
| Victoria Park | Sales Person | Connie | 1 | 1 |
| William Charlton | Jeff | Guy #2 | 1 | 1 |
| Audrey Moore | Susan | O.T.I. Lady | 1 | 1 |
| B.K. Cannon | Girl Band Geek | Heather | 1 | 1 |
| Cosima Cabrera | Paramedic #3 | Girl #1 | 1 | 1 |
| Ervin Ross | Emmett Lawson | Man #2 | 1 | 1 |
| Jane Morris | Ms. Goff | Waitress | 1 | 1 |
| Jason Boegh | Excited Doctor 1 | Ticket Buyer | 1 | 1 |
| Matthew Downs | Frank | Coach | 1 | 1 |
| Micah Nelson | Robbie Reeves | Aiden | 1 | 1 |
| Susan Grace | Jane | Female Customer | 1 | 1 |
| Suzanne Ford | Hazel Parker | Ms. Carrington | 1 | 1 |
| Amy Okuda | Chelsea Ansell | Opponent | 1 | 1 |
| Andy Kim | Father | Student | 1 | 1 |
| Betsy Baker | Barb | Patient | 1 | 1 |
| Brooke Baumer | Obstetrician | Margaret | 1 | 1 |
| Chiquita Fuller | Ashley Wright | Ms. Prescott | 1 | 1 |
| Jeremy Cohenour | Dr. Boyd | Tommy | 1 | 1 |
| Miya Horcher | James's Sister | Janie | 1 | 1 |
| Ping Wu | Seymour Glass | Mr. Yamamoto | 1 | 1 |
| Tammy Dahlstrom | Orderly | Carrie | 1 | 1 |
| Duane R. Shepard, Sr. | Trial Patient #5 | Judge | 1 | 1 |
| Jerry Kernion | Bobby Corso | Coach | 1 | 1 |
| Rob Mainord | Procurement Surgeon | Recruiter 1 | 1 | 1 |
| Ross Mackenzie | Dr. Mitchell | Waiter | 1 | 1 |
| Sarah Benoit | Nurse Julia Udell | Food Court Patron #4 | 1 | 1 |
| Taylor Mosby | Collegiate Bailey | Student #1 | 1 | 1 |
| Bob Rumnock | ND Doctor | Man | 1 | 1 |
| Nick Bush | Tenant | Employee | 1 | 1 |
| Cassandra Braden | Housekeeping Staffer | Woman | 1 | 1 |
| Eileen Fogarty | Mrs. Chen's Sister | Woman #1 | 1 | 1 |
| Heather Brooker | Daycare Worker #2 | Peggy | 1 | 1 |
| Toby Grey | Ernie | Axl's future son #1 | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.