All 80 actors in both Madam Secretary and Royal Pains
80 actors have appeared in both Madam Secretary and Royal Pains, across 224 episodes. The most-credited is Johanna Day, Admiral Ellen Hill in Madam Secretary and Elizabeth Dupont in Royal Pains.
| Actor | In Madam Secretary | In Royal Pains | Eps | Eps |
|---|---|---|---|---|
| Johanna Day | Admiral Ellen Hill | Elizabeth Dupont | 22 | 1 |
| Tracee Chimo | Nina Cummings | Lauren | 17 | 1 |
| Christine Ebersole | Lydia Dalton | Ms. Newberg | 4 | 13 |
| Tony Plana | Admiral Ed Parker | Marcos | 12 | 1 |
| Patrick Breen | Andrew Munsey | Therapist Bob | 7 | 6 |
| Justine Lupe | Captain Ronnie Baker | Cameron Krissy | 5 | 1 |
| Jason Kravits | Senator James Parisi | Dr. Dan Irving | 2 | 3 |
| Michael Mulheren | Barry Milken | Jim Harper | 1 | 6 |
| Peter Jacobson | Ted Rhodes | Alan Rider | 1 | 2 |
| Jeremy Davidson | Daryl Brennan | Ray Mazzarino | 2 | 6 |
| Kenya Brome | Keira Peters | EMT | 7 | 1 |
| Will Chase | Owen Callister | Ben Richards | 4 | 1 |
| Amanda Warren | Olivia Mason | Sandra | 6 | 1 |
| Anna Wood | Sarah Eckhart | Ana | 3 | 1 |
| John Cullum | Senator Beau Carpenter | Andres Bochinski | 5 | 1 |
| Lee Tergesen | Governor Richard Barker | Zack Kingsley | 2 | 1 |
| Michael Gaston | CIA Director Hugh Haymond | Ed Harper | 5 | 1 |
| David Furr | Agent Dan Santangelo | Bill Cartwright | 2 | 1 |
| Drew McVety | Captain | Bobby Moxley | 1 | 1 |
| Michael Potts | Fred Reynolds | Mr. Burman | 3 | 1 |
| Ronald Guttman | Klaus Von Muhlberg | Auction House Official | 2 | 1 |
| Michael Elian | Guy #1 | Mossad Guard | 1 | 5 |
| Florencia Lozano | Dr. Ruth Hubbard | Donald Green's agent | 2 | 1 |
| Lawrence Ballard | Officer Miller | Doctor Foley | 1 | 2 |
| Sharon Washington | Chelsea Weldon | Nurse Nancy | 1 | 2 |
| Alok Tewari | Iraqi Defense Minister Hasan | Dr. Alam Saba | 1 | 1 |
| David Rasche | Ambassador Arlen Maxwell | Charles Woodward | 1 | 1 |
| Francis Dumaurier | French President Léon Perrin | Lawyer #1 | 2 | 1 |
| Kevin Kilner | Robert Cole | Tom Seelig | 1 | 1 |
| Olga Merediz | Rep. Elle Vazquez | Esperanza | 1 | 1 |
| Robert Klein | Canadian Ambassador Lester Clark | Bert Jones | 1 | 1 |
| Sheila Tapia | Senator Linda Furey | Dr. Valerie Jory | 1 | 2 |
| Tom Patrick Stephens | Team Leader | Lyle McGillicuddy | 1 | 2 |
| Ato Essandoh | King Nungunde | Antoine | 1 | 1 |
| Berto Colón | Officer Freeman | EMT #2 | 1 | 1 |
| Margaret Colin | Judith Fanning | Lucy Everett | 1 | 1 |
| Patch Darragh | Scott | Felix | 1 | 1 |
| Rachel Hilson | Becca | Niece 1 | 1 | 1 |
| Cindy Katz | Diane Cramer | She | 2 | 1 |
| Hoon Lee | President Sung-Hoon Choi | Stu | 1 | 1 |
| Ken Marks | Senator Thornquist | Dr. Madden | 1 | 1 |
| Randall Newsome | General Ashtels | Dusty | 1 | 2 |
| Ray Iannicelli | Bob | Franco | 1 | 1 |
| William Abadie | Swiss Ambassador Claude Wuthrich | Javier Santos | 1 | 1 |
| AJ Cedeño | Senior MP | Lewis | 1 | 2 |
| Addison Lemay | Russian Man #2 | Security Guard | 1 | 1 |
| Bruce Altman | Alec Lehane | Jamie Zummerman | 1 | 1 |
| DeShawn Harold Mitchell | Special Ops Soldier | Orderly | 1 | 1 |
| Jorge Cordova | Miguel | Manager | 1 | 1 |
| Kate Jennings Grant | FBI Agent Teresa Pagani | Dr. Sylvander | 1 | 1 |
| Patrick Boll | FBI Agent #2 | Seersucker Man | 1 | 1 |
| Peter Francis James | Cyril Quist | Mackintosh | 1 | 1 |
| Tijuana Ricks | Rhonda Gunderson | Carrie | 1 | 1 |
| Almeria Campbell | Dr. Kerry Still | Kristen | 1 | 1 |
| Christine Toy Johnson | Kathy Akimoto | ER Doctor | 1 | 1 |
| Megan Byrne | Jessica Wellington | Hotel Clerk | 1 | 1 |
| Pippa Pearthree | Mary Curtis | Choir Member #1 | 1 | 1 |
| David Hess | Richard | Mr. Ambrose | 1 | 1 |
| Ed Moran | CIA Interrogator #1 | Captain Salmo | 1 | 1 |
| Jennifer Van Dyck | Cecilia Pedilla | Edwina | 1 | 1 |
| Kecia Lewis | Ms. Morales | Nurse | 1 | 1 |
| Laura Kai Chen | Lisa Wu | Mona Nguyen | 1 | 1 |
| Michael Bakkensen | Darren Taylor | Woody Keegan | 1 | 1 |
| Tom Galantich | Ramsey Peters | Doctor Post | 1 | 1 |
| Edelen McWilliams | Amy Ferber | Box Office Worker | 1 | 1 |
| Rob Breckenridge | CIA Agent | Sam Resnick | 1 | 1 |
| Hend Ayoub | Moussa's Wife | Delegate Amani | 1 | 1 |
| Marcus Ho | CIA Agent Sternwig | Greg | 1 | 1 |
| Matt Walton | Shawn Olson | Dennis 'DB' Brown | 1 | 1 |
| Nick Sullivan | Funeral Director | Choir Member #2 | 1 | 1 |
| Tina Chilip | Sonam Bhuti | Riza | 1 | 1 |
| Alexander Blaise | Yves Franz | Pilot | 1 | 1 |
| Danny Johnson | Gage Henriksen | Fire Chief | 1 | 1 |
| Miguel Cervantes | Pablo | Surfer | 1 | 1 |
| Tony Carlin | Senator McGrath | Dr. Starnes | 1 | 1 |
| Eva Kaminsky | Jenny Bach | Noelle | 1 | 1 |
| Stevie Steel | Gillian | Reed | 1 | 1 |
| Tatsuo Ichikawa | Tadao | Japanese Translator | 1 | 1 |
| Rona Figueroa | Reporter 2 | Surgical Tech | 1 | 1 |
| Don Guillory | EMT #2 | Dr. Wolf | 1 | 1 |
← Madam Secretary × Royal Pains
Cast data from TVmaze, licensed CC BY-SA 4.0.