All 299 actors in both Supernatural and The X-Files
299 actors have appeared in both Supernatural and The X-Files, across 545 episodes. The most-credited is Mitch Pileggi, Samuel Campbell in Supernatural and Assistant Director Walter Skinner in The X-Files.
| Actor | In Supernatural | In The X-Files | Eps | Eps |
|---|---|---|---|---|
| Mitch Pileggi | Samuel Campbell | Assistant Director Walter Skinner | 8 | 70 |
| Jim Beaver | Bobby Singer, Apocalypse World Bobby Singer | Coroner | 69 | 1 |
| William B. Davis | Professor | Cigarette-Smoking Man | 1 | 44 |
| Mark Sheppard | Crowley | Bob the Caretaker / Cecil L'Ively | 34 | 1 |
| Nicholas Lea | Elliot Ness | Agent Alex Krycek, Michael | 1 | 25 |
| Bruce Harwood | Professor William Hill | John Fitzgerald Byers | 1 | 38 |
| Steven Williams | Rufus Turner | Mr. X | 6 | 13 |
| Mark Pellegrino | Lucifer, Nick | Derwood Spinks | 15 | 1 |
| Bill Dow | Dr. Kadinsky, Mayor Chip Harrington | Dr. Charles Burks, Dad, Dr. Rick Newton | 2 | 9 |
| Ty Olsson | Benny Lafitte, Eli | Younger Orderly | 10 | 1 |
| Amanda Tapping | Naomi | Carina Sayles | 9 | 1 |
| Keith Szarabajka | Professor Donatello Redfield | Anthony Tipet | 9 | 1 |
| William MacDonald | Abraham Peterson, Sheriff | Agent Dan Kazanjian, Buddy Riggs, Dr. Oppenheim | 2 | 5 |
| Nicki Aycox | Meg Masters | Chastity Raines | 5 | 1 |
| A.J. Buckley | Ed Zeddemore | Dude | 4 | 1 |
| Karin Konoval | Mrs. Curry, Ruth | Little Chucky Poundstone, Little Judy Poundstone, Madame Zelma | 2 | 3 |
| Kevin McNulty | Phillip, Reverend Roy Le Grange | Agent Fuller, Dr. Christopher Davey | 2 | 3 |
| Alfred E. Humphreys | Sheriff | Dr. Mark Pomerantz, Michael Asekoff, Mission Controller #2 | 1 | 3 |
| Donnelly Rhodes | Father Simon, Mr. Shaw | General Francis, Jim Parker | 2 | 2 |
| Fiona Vroom | Dental Assistant, Nurse | Barbara Beaumont / Sitcom Barbara, Young Cassandra | 2 | 2 |
| Lynda Boyd | Dr. Jennifer O'Brien, Moira / Fortuna | Bar Patron, Elizabeth | 2 | 2 |
| Timothy Webber | Ranger Wilkinson | Detective Talbot, Dr. Paul Farraday, Jess Harold | 1 | 3 |
| Alex Bruhanski | Santa Village Santa | Angelo Pintero, Dr. Bugger | 1 | 2 |
| Chad Lindberg | Ash | Bobby Rich | 5 | 1 |
| Darren Dolynski | Captain James Dearborn, Demon | Man in Suit | 2 | 1 |
| Fredric Lehne | Yellow-Eyed Demon | Arthur Dales | 4 | 2 |
| Genevieve Buechner | Lily Shoemaker, Samantha | Kayla | 2 | 1 |
| Ian Tracey | Ishim, Lee Chambers | Sergeant Leonard 'Rappo' Trimble | 2 | 1 |
| Jon Gries | Martin Creaser | Salvatore Matola | 2 | 1 |
| Katharine Isabelle | Ava Wilson | Lisa Baiocchi | 2 | 1 |
| Teryl Rothery | Coroner, Olivette | Nurse Michelle Charters | 2 | 1 |
| Chilton Crane | Helen Kline, Beverly Tanner, Mary Lew | Sharon Graffia, Margaret Hohman, Mother at Bus Station | 4 | 4 |
| Emily Perkins | Becky Rosen | Dara Kernof / Paula Koklos / Roberta Dyer | 4 | 1 |
| Hrothgar Mathews | Grossman | Creighton Jones, Galen Muntz, Jack | 1 | 4 |
| Andrew Airlie | Henry Whitman, Larry Pike | Attorney, Rob | 2 | 2 |
| Benito Martinez | Edgar | Orderly | 5 | 1 |
| Brian Markinson | Jerry Panowski, Stan Thompson | Gary Lambert, Tony Fiore | 2 | 2 |
| Catherine Lough Haggquist | Detective Glass, Jules, Hunter | Dr. Richmond | 5 | 1 |
| David Cubitt | Barthamus | Captain Barclay | 1 | 1 |
| Hiro Kanagawa | Game Show Host | Dr. Yonechi, Garner, Peter Tanaka | 1 | 3 |
| Jay Brazeau | Dr. Corman, Researcher | Dr. Daly, Professor Varnes | 2 | 2 |
| Jewel Staite | Amy Pond | Amy Jacobs | 1 | 1 |
| John DeSantis | Freeman Daggett, Moloch, The Golem | Band-Aid Nose Man | 3 | 1 |
| Linden Banks | Isaiah Merchant, Mr. Brennan | Joseph Patnik, Reverend Sistrunk | 2 | 2 |
| Malcolm Stewart | Dr. Aaron Fuller | Dr. Sacks, Agent Bonnecaze, Commander Carver | 1 | 5 |
| Mark Rolston | Alastair | Bud LaPierre, Richard Odin | 2 | 2 |
| Ryan Robbins | Travis Wheeler | Murphy | 1 | 1 |
| Sarah Jane Redmond | Kathy Randolph, Lily Markham | Karin Matthews, Young Mother | 2 | 2 |
| Titus Welliver | Roger / War | Doug Spinney | 1 | 1 |
| Alex Diakun | Grim Reaper, Mr. Vili | Buddy / Devil, Curator, Dr. Fingers | 2 | 5 |
| Christine Willes | Grandmother Nickerson | Agent Karen Kossef, Sister Mary | 1 | 4 |
| Steve Bacic | Dr. Sexy, Pastor Joe Robles | Agent Collins, Officer #2, S.W.A.T. Commander | 2 | 3 |
| Tom McBeath | Jack, Mr. Carey | Detective Gwynn, Dr. Lewton, Scientist | 2 | 3 |
| Gillian Barber | Dr. Hess, Mrs. Rourke | Penny Northern, Agent Jane Spiller, Beth Kane | 4 | 4 |
| Aliza Vellani | Beth Roberts | Nurse Sandeep | 1 | 2 |
| Alvin Sanders | Jimmy Anderson | Bus Driver, Deputy Wright | 1 | 2 |
| Blu Mankuma | Dr. Jennings | Claude Peterson, Det. Pennock | 1 | 2 |
| Brent Stait | Joey Six, Rick, Scotty | Timothy Mayhew, Corp. Taylor | 3 | 3 |
| Callum Keith Rennie | Roy | Groundskeeper, Tommy Philips | 1 | 2 |
| Daryl Shuttleworth | Captain Chuck Lambert, Sheriff Rick Carnegie | Daryl Landry | 2 | 1 |
| Don S. Davis | Trotter | Captain William Scully | 1 | 2 |
| Forbes Angus | Foster, Max Alexander | Funeral Director, Government Scientist, M.D. | 2 | 4 |
| Johnny Cuthbert | Alvin Jenkins | Commanding Officer, Tiernan | 1 | 2 |
| Madeleine Arthur | Young Tina | Sarah Arthur | 1 | 2 |
| Michael B. Silver | Martin | Howard Grodin | 1 | 2 |
| Michael Massee | Kubrick | Vernon Ephesian | 2 | 1 |
| Sebastian Spence | Assistant Demon | Deputy Barney Paster | 2 | 1 |
| Steve Railsback | Joseph Welch | Duane Barry | 1 | 2 |
| Tom O'Brien | Clark Adams | Corporal Frish | 1 | 2 |
| Doug Abrahams | Detective Howard, Eddie | Agent #2, Detective Neary, Farbaugh | 2 | 5 |
| Ben Cotton | Businessman/Pride, Garret Weiler / Richard Beesom | Mr. Paulsen | 2 | 2 |
| David Lewis | Professor Ludensky | Vosberg, Young Agent, Young Officer | 1 | 3 |
| Fred Henderson | Preacher, Security Guard | Agent Rich, Agent Thomas | 2 | 2 |
| Robert Moloney | Peter Warren, Rudy | Bruce Bearfeld, Worker | 2 | 2 |
| Veena Sood | Dr. Aldrich, Principal Ramirez | Dr. Louise Colquitt, Mrs. Saunders | 2 | 2 |
| Wolsey Brooks | Wounded Refugee Hunter | FBI Agent #2 | 3 | 1 |
| Barry W. Levy | Smithy | Vitagliano, Navy Doctor | 2 | 3 |
| Don Thompson | Mr. Guenther, Sheriff Jake Miller | Henry Willig, Holtzman, Lieutenant Colonel Victor Stans | 2 | 3 |
| Megan Leitch | Female Driver | Samantha Mulder | 1 | 4 |
| Veronica Cartwright | Lily Sunder | Cassandra Spender | 1 | 4 |
| Eric Breker | Alternate Universe Hunter, Police Officer | Dark-Suited Man #1, Admitting Officer, SP Agent Brem | 2 | 4 |
| Ken Camroux-Taylor | Genital Herpes Older Man, Mr. D | Senior Agent #2 | 2 | 5 |
| Anja Savcic | Girl #2, Reese | Girl | 2 | 1 |
| Bellamy Young | Lucifer / Sarah | Janet Wilson | 1 | 1 |
| Ben Wilkinson | Philippe, Trey | Dean Cavalier | 2 | 1 |
| Billy Drago | Doc Benton | Mr. Peattie | 1 | 1 |
| Carlena Britch | Miriam | Juliet "La Avispa" Bocanegra | 1 | 1 |
| Colin Lawrence | Dr. Gregory Marion, Jason, Reggie Hull | Cop #1 | 3 | 1 |
| Colleen Winton | Mrs. Lloyd | Lie Detector Technician, Therapist | 1 | 2 |
| Colton James | Gary Finkel | Josh Underwood | 1 | 1 |
| Duncan Fraser | Clive Dillon, Odin | Beatty | 2 | 1 |
| Gardiner Millar | Bouncer/Wrath, Marv | Eugene Baiocchi, Man in Suit | 2 | 2 |
| Gary Hetherington | Mayor Harold Todd | Kennedy, Lewin | 1 | 2 |
| George Touliatos | Larry Ganem | Dr. Katz, Larry Winter | 1 | 2 |
| Glynis Davies | Mrs. Kemper | Ellen, Monica Landis, Nelson | 1 | 3 |
| Guyle Fraizer | Priest | Barney, Officer | 1 | 2 |
| James Otis | Famine | Arlen Sacks | 1 | 1 |
| Janet Kidder | Amanda Duren | Nurse | 1 | 1 |
| Jennifer Clement | Wendy Rice | Michele Wilkes | 1 | 1 |
| Ken Tremblett | Ron, Trooper Jack Spradlin | Dyer, Uniformed Officer | 2 | 2 |
| Lorena Gale | Landlady | Attorney, Ellen Bledsoe, Nurse Wilkins | 1 | 3 |
| Mark Acheson | Hansel, Tooth Fairy | Ted Bertram, Trucker | 2 | 2 |
| Merrilyn Gann | Madge Carrigan | Mrs. Asekoff, Prosecutor | 1 | 2 |
| Robert Curtis Brown | Father Gil | Assistant DA Damon Kaylor | 1 | 1 |
| Sean Campbell | Police Officer, Sheriff, Steve | Local Cop, Officer Sean | 3 | 2 |
| Sharon Taylor | Ardat, Female Demon | Diana Eggers | 2 | 1 |
| Stephen E. Miller | Okey Dokey Guard | Coroner Truitt, Tactical Commander | 1 | 2 |
| Terry David Mulligan | Randy Baxter | Mission Controller #1 | 1 | 1 |
| Tom Butler | Harley Jorgeson, Reverend Jim Meyers | Benjamin Drake, CIA Agent Ambrose Chapel | 2 | 2 |
| Tom Pickett | Angel Soldier, Lt. Danny Gunderson | Cop | 2 | 1 |
| Viv Leacock | Gerald, Jim's Friend | Price | 3 | 1 |
| Xantha Radley | Homeless Woman, Shelley | Waitress | 2 | 1 |
| Brent Chapman | Ed the Superintendant, Paul Hayes | Security Cop, Traffic Cop | 2 | 2 |
| Dean Aylesworth | Pete | Young Bill Mulder | 1 | 3 |
| Dean Wray | Driver #1, Sheriff | Rich Turner, Tow Truck Driver | 2 | 2 |
| Dmitry Chepovetsky | Nikolai Lishin | Government Man #1, Lt. Richard Harper, Supervisor | 1 | 3 |
| Eileen Pedde | Dr. Kessler, Mrs. Finkel | Angie, Mrs. Skur | 2 | 2 |
| Fulvio Cecere | Cromarty, Strip Club Owner | Aide, Priest | 2 | 2 |
| Kurt Evans | Special Agent Carl Reidy, Marnie's Husband | Sports Store Employee | 3 | 1 |
| BJ Harrison | Shapeshifter | Clerk, Hannah | 1 | 2 |
| Kwesi Ameyaw | Dr. Lewis, Professor | Judge | 2 | 1 |
| Anthony Harrison | Captive Demon, Sal Moriarty | 4th Man, Agent Riggins | 2 | 2 |
| Chris Shields | Niveus Doctor #2 | Detective Dross | 1 | 1 |
| Dalias Blake | Policeman | Cop #2 | 1 | 1 |
| Dan Butler | Reverend Sorenson | Jim Ausbury | 1 | 1 |
| Danielle Savre | Margo Lassiter | Marcia Brady | 1 | 1 |
| Derek Lowe | EMT | Johnny Lo | 1 | 1 |
| Emma Oliver | Gertie Fitzgerald | Emily Strong | 1 | 1 |
| Hank Harris | Gerry / Boltar the Furious | Dylan Lokensgard | 1 | 1 |
| Jamil Walker Smith | Luis | Chester Bonaparte | 1 | 1 |
| Jeff Kober | Randall | Bear | 1 | 1 |
| Jill Teed | Madeleine | Glenna | 1 | 1 |
| Kacey Rohl | Marin | Agnes | 1 | 1 |
| Ken Kramer | Mr. Cooper | Dr. Alexander Ivanov, Dr. Browning, Dr. Terrance Allen Berube | 1 | 3 |
| Laurie Paton | Lorraine Fox | Lady Marsden | 1 | 1 |
| Murray Lowry | Bartender | Fisherman | 1 | 1 |
| P. Lynn Johnson | Stacey Jorgeson | Deborah Brown, Dr. Sheila Braun, Health Department Doctor | 1 | 3 |
| R.D. Call | Sheriff Pierce | Sheriff Maurice Daniels | 1 | 1 |
| Rob LaBelle | Father Lehne / Azazel | Brad Wilczek | 1 | 1 |
| Spencer Garrett | Edward Carrigan | Harry Bring | 1 | 1 |
| William S. Taylor | Detective | General Leitch | 1 | 1 |
| Alison Araya | Jolene, Vice Principal Bailey | Nurse Vickie Easton | 2 | 1 |
| Eric Keenleyside | Dennis, Jim McAnn | Lance Kernof | 2 | 1 |
| Fred Keating | Jack Kline, Neighbor | Detective Ray Thomas | 2 | 1 |
| Giacomo Baessato | Daniel, Pizza Delivery Guy | Doctor | 2 | 1 |
| John Trottier | Wayne McNut | Clinician #3, George Peacock | 1 | 2 |
| Julian D. Christopher | Doctor 2, Warren | Dr. Oscar Griffiths | 2 | 1 |
| Paul McGillion | Jim Grossman, Peter Harper | Fred Neiman | 2 | 1 |
| Stefan Arngrim | Redcap | Prisoner | 1 | 2 |
| Stephen Lobo | Rick Sanchez | Dark-Suited Man #1 | 2 | 1 |
| Roger Haskett | Dr. Paul Conley, Joe McKinley | Coroner, Deputy Tyson | 2 | 2 |
| Aidan Kahn | Duke | Agent Colquitt | 1 | 1 |
| Albert Nicholas | Jonah | Agent Bill Bludworth | 2 | 1 |
| Alessandro Juliani | Adam | Joseph Cutler | 1 | 1 |
| Benita Ha | Veterinarian | Tour Guide | 1 | 1 |
| Bethoe Shirkoff | Mrs. Sweeney | Old Woman | 1 | 1 |
| Billy Wickman | Brian, Elvis Katz | Pick Up Driver | 2 | 1 |
| Brad Loree | Police Officer | Fireman, Security Guard | 1 | 2 |
| C. Ernst Harth | Heavyset Man/Sloth | Huge Man | 1 | 1 |
| Cameron McDonald | Jim Miller | Father Hardy | 1 | 1 |
| Chad Willett | Mr. Wyatt | Jim Summers | 1 | 1 |
| Craig March | Frank Kellog, Man | Detective Gordon | 2 | 1 |
| Douglas Roy Dack | Biker | Mighty Man | 1 | 1 |
| Gerard Plunkett | Plutus | Dr. Calderon | 1 | 2 |
| Henri Lubatti | Reaper | Dr. Wilkenson | 1 | 1 |
| Ian Robison | Hank | Detective Smith, Ranger | 1 | 2 |
| J. Alex Brinson | Dax | FBI Agent Guard | 1 | 1 |
| Jase Anthony Griffith | Sheriff | Paramedic #1 | 1 | 1 |
| Jerry Wasserman | Coroner | Dr. John Grago, Dr. Plith | 1 | 2 |
| Jimmy Herman | Joe White Tree | Ish | 1 | 1 |
| Mar Andersons | Future Prophet | Halverson, Jack Hammond | 1 | 2 |
| Megan Peta Hill | Kylie | Molly | 1 | 1 |
| Michael Rogers | Bartender/Gluttony, Irv | Crewman #1, Lt. Griffin | 2 | 2 |
| Richard Newman | Oliver Bryce | Dr. Rumanovitch | 1 | 1 |
| Rick Dobran | Homeless Man | Sergeant Armando Gonzales | 1 | 2 |
| Russell Porter | Ronnie Cartwright, Sid | Scott Simmons | 2 | 1 |
| Scott Hylands | Judge Tye Mortimer | General Benjamin Bloch | 1 | 1 |
| Terence Kelly | Daniel Elkins, Hospital Doctor | George Usher | 2 | 1 |
| Todd Mann | Gerald Hatch, Tough Guy #1 | FBI Agent #2 | 2 | 1 |
| Gerry Rousseau | Bill Gibson, Billy Beaird | Homeless Man, Mechanic | 2 | 2 |
| Bill Croft | Farmer | Calusari #2, Comrade Svo | 1 | 2 |
| Brenda McDonald | Rose Thompson | Auntie Janet, Mrs. Loach | 1 | 2 |
| Garvin Cross | Mr. Pogue | Red Head Kid, Repairman | 1 | 2 |
| J. Douglas Stewart | Sheriff | Landlord, Male E.M.T. | 1 | 2 |
| Ken Roberts | Old Coot | Clerk, Proprietor | 1 | 2 |
| Laurie Murdoch | Mr. Tanner | Coroner, Lydon | 1 | 2 |
| Marc Baur | Officer Toby Grey | Agent Brisentine, Man in Suit | 1 | 2 |
| Patrick Keating | Joke Shop Owner | Beggar, Donald Gelman | 1 | 2 |
| Paul Jarrett | George Phelps | James Earl Ray, Upshaw | 1 | 2 |
| Peter Hanlon | Tom Wepram | Aide, Dr. Bailey | 1 | 2 |
| Ted Cole | Coroner, Partygoer | 2nd Paramedic | 2 | 1 |
| Tim Dixon | Priest | Bob, Dr. Richard W. Godfrey | 1 | 2 |
| Aaron Douglas | Pierce Moncrieff | Lindquist | 1 | 1 |
| Daniela Dib | Devil Dancer | Sarah | 1 | 1 |
| David Abbott | Dexter Hasselback | Judge Maibaum | 1 | 1 |
| Dean McKenzie | Eremiel | Army Tech | 1 | 1 |
| Ellie Harvie | Coroner Shelly | OPO Staffer | 1 | 1 |
| Garry Chalk | Sheriff Deitrich | Mad Dog | 1 | 1 |
| Jillian Fargey | Deb | Kaye Schilling | 1 | 1 |
| John R. Taylor | Sherwin | Husband | 1 | 1 |
| Ken Kirzinger | Jared Bender | Richter | 1 | 1 |
| Nancy J. Lilley | Leann Rayburn | Liposuction Patient | 1 | 1 |
| Peter Anderson | Convenience Store Clerk | Stan Buxton | 1 | 1 |
| Peter Bryant | Deputy Walt Fanningham | Uniformed Cop | 1 | 1 |
| Richard Yee | Gorgon Victim | David Yung | 1 | 1 |
| Ryan Hesp | Kabaiel | Henchman #1 | 1 | 1 |
| Beatrice Zeilinger | Sheriff Adams | Burly Nurse, Paramedic | 1 | 2 |
| Bill Mackenzie | Short Order Cook | Bus Driver | 1 | 2 |
| Nancy Kerr | Wendy | Agent Hedin, Nurse | 1 | 2 |
| Norman Armour | Dr. Sanford Ellicott | Coroner, E.R. Doctor | 1 | 2 |
| Stephen Dimopoulos | Restaurant Owner | Detective, Ionesco | 1 | 2 |
| Alison Wandzura | EMT | Cynthia | 1 | 1 |
| Debs Howard | Julie | Girl #2 | 1 | 1 |
| Denalda Williams | Doris | Madame Zirinka, Marilyn | 1 | 2 |
| Iris Quinn | Barbara Cordry | Lillian Daniels | 1 | 1 |
| Jay Hindle | Man, Rod | Sitcom Joe | 2 | 1 |
| John Tench | Ellsworth | Steve | 1 | 1 |
| Jonathan Lloyd Walker | Beau | Chuck Lukerman | 1 | 1 |
| Kimberly Unger | Rick's Wife | Joan Gauthier, Karen Koretz | 1 | 2 |
| Kurt Max Runte | Sgt. Tucker, Sheriff Lee | Ranger | 2 | 1 |
| Lori Ann Triolo | Head Nurse | Diane | 2 | 1 |
| Mackenzie Murdock | Demon Victim, Giggling Demon | Gas Attendant | 2 | 1 |
| Mike Dopud | Jim Jenkins | Mr. Y's Henchman | 1 | 1 |
| Ralph Alderman | Morgue Attendant | Manager | 1 | 1 |
| Robert Peters | Deputy Hein | Sergeant | 1 | 1 |
| Robert Rozen | Cupid | Doctor, Dr. Alton Pugh | 1 | 2 |
| Ryan Beil | Set Guy | Werelizard | 1 | 1 |
| Simon Longmore | Barricade Guard | Marty Fox | 1 | 1 |
| Sunita Prasad | Serena Colman | Dr. Aliyeh Scholtz | 1 | 1 |
| Thomas Nicholson | Daniel Singer | BDU Soldier | 1 | 1 |
| Paul Batten | Sheriff | Brother Wilson, Dr. Seizer | 1 | 2 |
| Aiden Longworth | Tyler | William (10 & 13 yr old) | 1 | 1 |
| Alison Matthews | Frannie Wandel | Doctor | 1 | 1 |
| Barbara Pollard | Neighbor Lady | Gwen | 1 | 1 |
| Bob Frazer | Rosco | Gary Kane | 1 | 1 |
| Eddie Flake | Deputy Coroner | D.O.D. Operative | 1 | 1 |
| Frank Cassini | Detective | Detective Cline | 1 | 1 |
| Glenn Williams | Cop | Officer | 1 | 1 |
| Jason Schombing | Shawn Russo | Warren James Dupre | 1 | 1 |
| Jo-Ann Fernandes | Consuela Alvarez | Forensic Technician | 1 | 1 |
| Marcus Hondro | Demon | Barber | 1 | 1 |
| Naiah Cummins | Confused Person | Nurse | 1 | 1 |
| Nikolai Witschl | Coroner | Dr. Hill | 1 | 1 |
| Paula Shaw | Grandma Demon | Ward Nurse | 1 | 1 |
| Richard Sali | Pastor Jim Murphy | Leon Felder | 1 | 1 |
| Saraphina Joachim | Skeptical Pedestrian | Jennifer Workman | 1 | 1 |
| Seth Whittaker | Cook | Fitzpatrick | 1 | 1 |
| Thabo Ketshabetswe | Mitch | Guard | 1 | 1 |
| Tony Morelli | Gunshot Victim | Cop | 1 | 1 |
| Frank C. Turner | Elkins | Dr. Collins, Dr. Del Hakkie | 1 | 2 |
| Kathleen Duborg | Head Secret Service Agent | Mother, Prostitute | 1 | 2 |
| Andy Thompson | Librarian | Customs Agent | 1 | 1 |
| Anjali Jay | Dr. Kashi | Dr. Joyet | 1 | 1 |
| Antonio Cayonne | Daniel | FBI Agent #1 | 1 | 1 |
| Aurelio DiNunzio | Detective Sutton | Detective | 1 | 1 |
| Christopher Logan | Demon | Dr. Sanjay | 1 | 1 |
| David Lovgren | Charlie Holt | Kurt Crawford | 1 | 1 |
| Garrett Black | Minion #1 | Technician | 1 | 1 |
| Henry Mah | Coroner | Night Manager | 1 | 1 |
| Jannen Karr | Principal Salazar | Nurse Taillie | 1 | 1 |
| Jason Diablo | Cal Garrigan | Angry Man | 1 | 1 |
| Lloyd Berry | Mr. Pickett | Old Man | 1 | 1 |
| Marci T House | Nurse | Angry Woman | 1 | 1 |
| Michael Kopsa | Sheriff | Rick Culver | 1 | 1 |
| Mik Byskov | Angel #1 | Accosting Man | 1 | 1 |
| Nneka Croal | Coroner | Squad Leader | 1 | 1 |
| Patti Allan | Madeline Hackett | Mrs. Kernof | 1 | 1 |
| Phil Hayes | Clif | Driver | 1 | 1 |
| R. Nelson Brown | Gerard St. James / Frank Jaffy | Ansel Bray | 1 | 1 |
| Rob Morton | Sheriff | Kramer | 1 | 1 |
| Robert Underwood | Lance Lacroix | Paramedic | 1 | 1 |
| Steve Adams | Policeman | Myers | 1 | 1 |
| Tim Henry | Dirk McGregor Sr. | Federal Marshall, Plain-Clothed Man | 1 | 2 |
| Travis MacDonald | Guy at Bar | Dave Duran | 1 | 1 |
| Shaine Jones | Asa Fox, Demon Medic | Dark-Suited Man #2 | 2 | 1 |
| David Bloom | Curator | Stress Man | 1 | 1 |
| David Neale | Ben Waters | Navy Base Guard | 1 | 1 |
| Omari Newton | Peter Kent Demon | Rogers | 1 | 1 |
| Shane Dean | Dipper | Henchman #2 | 1 | 1 |
| Thomas Newman | Salinger | FBI Agent #1 | 1 | 1 |
| Danny Wattley | Front Desk Security Guard | First Officer | 1 | 1 |
| Frank Ferrucci | Security Guard Demon | Detective Nettles | 1 | 1 |
| Robert Mann | Frank | Hillbilly Ed | 1 | 1 |
| Sachin Sahel | Senator's Aide | Jack Budd | 1 | 1 |
| Simon Chin | Prison Guard | Janitor #2 | 1 | 1 |
| Troy Anthony Young | Reg | Mr. Van De Kamp | 1 | 1 |
| Wren Robertz | Brad | Orderly | 1 | 1 |
| Artin John | Demon Technician | Shiraz | 1 | 1 |
| David Livingstone | Gandhi | Guard | 1 | 1 |
| Hannah Longworth | Delilah | William (6 yr old) | 1 | 1 |
| Rhett Spencer | Vampire | First Dude | 1 | 1 |
| Shaker Paleja | Insurance Representative | O.R. Surgeon | 1 | 1 |
| Cam Cronin | Doctor 6 | Paramedic | 1 | 1 |
| Guy Fauchon | Head Waiter Marty | Dr. Dave Rednon | 1 | 1 |
| James R. Baylis | Guardian Demon | Homeless #1 | 1 | 1 |
| Kim Kondrashoff | Clem Smedley | Bobby Torrence | 1 | 1 |
| Michael Q. Adams | Male Demon | Pastor | 1 | 1 |
| Dean Redman | Second Girl's Father | Police Officer | 1 | 1 |
| Shane Symons | Shapeshifter | Other Marine | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.